14-3-3 ζ Antibody (G-2): sc-518031
- 14-3-3 ζ Antibody (G-2) is a mouse monoclonal IgG3 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 122-140 within an internal region of 14-3-3 ζ of human origin
- Anti-14-3-3 zeta Antibody (G-2) is recommended for detection of 14-3-3 ζ and, to a lesser extent, 14-3-3 ε of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-14-3-3 zeta Antibody (G-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for 14-3-3 ζ Antibody (G-2). This work is in progress.
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SEE ALSO...
14-3-3 ζ Antibody (G-2) is a mouse monoclonal IgG3 kappa light chain antibody that detects 14-3-3 ζ protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-14-3-3 ζ antibody (G-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. 14-3-3 ζ protein plays a crucial role in regulating cellular processes such as apoptosis, mitogenic signaling, and cell-cycle checkpoints, which are particularly relevant in cancer biology. As part of a family of seven isoforms, including 14-3-3 β, γ, ε, ζ, η, θ, and σ, 14-3-3 proteins function by forming dimers that create two binding sites for ligand proteins, facilitating interactions that may not occur otherwise. These proteins primarily recognize a consensus binding motif characterized by serine/threonine phosphorylation, allowing them to regulate a wide array of cellular functions. 14-3-3 ζ protein′s ability to sequester proteins in the cytoplasm, occupy interaction domains, and modulate enzymatic activity underscores its importance in maintaining cellular homeostasis. Disruption of 14-3-3 ζ expression can lead to various pathological conditions, highlighting its significance in cellular signaling pathways and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
14-3-3 ζ Antibody (G-2) | sc-518031 | 200 µg/ml | $316.00 | |||
14-3-3 ζ Antibody (G-2) AC | sc-518031 AC | 500 µg/ml, 25% agarose | $416.00 | |||
14-3-3 ζ Antibody (G-2) HRP | sc-518031 HRP | 200 µg/ml | $316.00 | |||
14-3-3 ζ Antibody (G-2) FITC | sc-518031 FITC | 200 µg/ml | $330.00 | |||
14-3-3 ζ Antibody (G-2) PE | sc-518031 PE | 200 µg/ml | $343.00 | |||
14-3-3 ζ Antibody (G-2) Alexa Fluor® 488 | sc-518031 AF488 | 200 µg/ml | $357.00 | |||
14-3-3 ζ Antibody (G-2) Alexa Fluor® 546 | sc-518031 AF546 | 200 µg/ml | $357.00 | |||
14-3-3 ζ Antibody (G-2) Alexa Fluor® 594 | sc-518031 AF594 | 200 µg/ml | $357.00 | |||
14-3-3 ζ Antibody (G-2) Alexa Fluor® 647 | sc-518031 AF647 | 200 µg/ml | $357.00 | |||
14-3-3 ζ Antibody (G-2) Alexa Fluor® 680 | sc-518031 AF680 | 200 µg/ml | $357.00 | |||
14-3-3 ζ Antibody (G-2) Alexa Fluor® 790 | sc-518031 AF790 | 200 µg/ml | $357.00 |