GHITM is implicated in the regulation of mitochondrial morphology and function, and the chemicals listed above are thought to influence GHITM activity indirectly by modulating various aspects of mitochondrial dynamics and function. Mdivi-1 and CCCP, for instance, affect mitochondrial division and membrane potential, respectively, and can thus impact the role of GHITM in mitochondrial morphology. Oligomycin and Antimycin A, which inhibit different components of the mitochondrial electron transport chain, can influence mitochondrial ATP production and respiration, potentially affecting GHITM's functionality.
Resveratrol and Metformin are known to modulate mitochondrial biogenesis and overall function, which could have downstream effects on GHITM. Similarly, Bongkrekic Acid and Rotenone alter mitochondrial function through their actions on the adenine nucleotide translocator and complex I of the electron transport chain, respectively. FCCP and Rapamycin, with their roles in mitochondrial uncoupling and mTOR signaling, can also indirectly impact GHITM activity. Lastly, compounds like Nicotinamide Mononucleotide (NMN) and Coenzyme Q10, which are involved in enhancing mitochondrial biogenesis and function, may also influence the activity of GHITM. These compounds serve as important tools for probing the functional roles of GHITM in mitochondrial dynamics and for understanding how mitochondrial function is integrated with broader cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Mdivi-1 is a mitochondrial division inhibitor that may indirectly affect GHITM by influencing mitochondrial fission and fusion dynamics. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $77.00 $153.00 $240.00 | 8 | |
CCCP is a mitochondrial uncoupler that can potentially influence GHITM activity by disrupting mitochondrial membrane potential. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Oligomycin, an ATP synthase inhibitor, might indirectly affect GHITM by altering mitochondrial ATP production and overall mitochondrial function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can modulate mitochondrial function and biogenesis, potentially influencing GHITM's role in mitochondrial dynamics. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin, primarily known for its role in diabetes management, can also affect mitochondrial function, potentially impacting GHITM activity. | ||||||
Bongkrekic acid | 11076-19-0 | sc-205606 | 100 µg | $400.00 | 10 | |
Bongkrekic Acid inhibits mitochondrial adenine nucleotide translocator, potentially affecting GHITM by altering mitochondrial membrane potential and function. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
NMN, a NAD+ precursor, can enhance mitochondrial function and biogenesis, possibly influencing GHITM activity. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Rotenone, a mitochondrial complex I inhibitor, may indirectly affect GHITM by impacting mitochondrial electron transport chain activity. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Antimycin A, a complex III inhibitor of the mitochondrial electron transport chain, can potentially influence GHITM activity by affecting mitochondrial respiration. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $94.00 $355.00 | 46 | |
FCCP is another mitochondrial uncoupler that may indirectly affect GHITM by altering mitochondrial membrane potential and function. | ||||||