Date published: 2026-5-30

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GHITM Activators

GHITM is implicated in the regulation of mitochondrial morphology and function, and the chemicals listed above are thought to influence GHITM activity indirectly by modulating various aspects of mitochondrial dynamics and function. Mdivi-1 and CCCP, for instance, affect mitochondrial division and membrane potential, respectively, and can thus impact the role of GHITM in mitochondrial morphology. Oligomycin and Antimycin A, which inhibit different components of the mitochondrial electron transport chain, can influence mitochondrial ATP production and respiration, potentially affecting GHITM's functionality.

Resveratrol and Metformin are known to modulate mitochondrial biogenesis and overall function, which could have downstream effects on GHITM. Similarly, Bongkrekic Acid and Rotenone alter mitochondrial function through their actions on the adenine nucleotide translocator and complex I of the electron transport chain, respectively. FCCP and Rapamycin, with their roles in mitochondrial uncoupling and mTOR signaling, can also indirectly impact GHITM activity. Lastly, compounds like Nicotinamide Mononucleotide (NMN) and Coenzyme Q10, which are involved in enhancing mitochondrial biogenesis and function, may also influence the activity of GHITM. These compounds serve as important tools for probing the functional roles of GHITM in mitochondrial dynamics and for understanding how mitochondrial function is integrated with broader cellular processes.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mdivi-1

338967-87-6sc-215291
sc-215291B
sc-215291A
sc-215291C
5 mg
10 mg
25 mg
50 mg
$67.00
$126.00
$251.00
$465.00
13
(2)

Mdivi-1 is a mitochondrial division inhibitor that may indirectly affect GHITM by influencing mitochondrial fission and fusion dynamics.

Carbonyl Cyanide m-Chlorophenylhydrazone

555-60-2sc-202984A
sc-202984
sc-202984B
100 mg
250 mg
500 mg
$77.00
$153.00
$240.00
8
(1)

CCCP is a mitochondrial uncoupler that can potentially influence GHITM activity by disrupting mitochondrial membrane potential.

Oligomycin

1404-19-9sc-203342
sc-203342C
10 mg
1 g
$149.00
$12495.00
18
(2)

Oligomycin, an ATP synthase inhibitor, might indirectly affect GHITM by altering mitochondrial ATP production and overall mitochondrial function.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol can modulate mitochondrial function and biogenesis, potentially influencing GHITM's role in mitochondrial dynamics.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

Metformin, primarily known for its role in diabetes management, can also affect mitochondrial function, potentially impacting GHITM activity.

Bongkrekic acid

11076-19-0sc-205606
100 µg
$400.00
10
(1)

Bongkrekic Acid inhibits mitochondrial adenine nucleotide translocator, potentially affecting GHITM by altering mitochondrial membrane potential and function.

β-Nicotinamide mononucleotide

1094-61-7sc-212376
sc-212376A
sc-212376B
sc-212376C
sc-212376D
25 mg
100 mg
1 g
2 g
5 g
$110.00
$150.00
$220.00
$300.00
$600.00
4
(1)

NMN, a NAD+ precursor, can enhance mitochondrial function and biogenesis, possibly influencing GHITM activity.

Rotenone

83-79-4sc-203242
sc-203242A
1 g
5 g
$89.00
$259.00
41
(2)

Rotenone, a mitochondrial complex I inhibitor, may indirectly affect GHITM by impacting mitochondrial electron transport chain activity.

Antimycin A

1397-94-0sc-202467
sc-202467A
sc-202467B
sc-202467C
5 mg
10 mg
1 g
3 g
$55.00
$63.00
$1675.00
$4692.00
51
(1)

Antimycin A, a complex III inhibitor of the mitochondrial electron transport chain, can potentially influence GHITM activity by affecting mitochondrial respiration.

FCCP

370-86-5sc-203578
sc-203578A
10 mg
50 mg
$94.00
$355.00
46
(1)

FCCP is another mitochondrial uncoupler that may indirectly affect GHITM by altering mitochondrial membrane potential and function.