Carbonyl Cyanide m-Chlorophenylhydrazone (CAS 555-60-2)

Carbonyl Cyanide m-Chlorophenylhydrazone (CCCP) is a versatile synthetic compound extensively utilized in scientific research. It exists as a colorless solid, soluble in polar organic solvents, and finds wide applications in synthetic organic chemistry and medicinal chemistry as an intermediate in drug synthesis. Carbonyl Cyanide m-Chlorophenylhydrazone exhibits various biochemical and physiological effects, including inhibiting enzymes involved in prostaglandin synthesis and cyclooxygenase activity. It has demonstrated anti-inflammatory, analgesic, and anti-tumor properties. Moreover, Carbonyl Cyanide m-Chlorophenylhydrazone has been employed in numerous scientific research applications, exploring its impact on drugs, cells, and tissues. While its mechanism of action is not fully understood, it is believed to hinder prostaglandin synthesis enzymes and competitively inhibit cyclooxygenase, for prostaglandin production. Additionally, Carbonyl Cyanide m-Chlorophenylhydrazone serves as a proton ionophore and is employed as an uncoupling agent and inhibitor of photosynthesis due to its effects on mitochondrial and chloroplast membranes. It acts as an inhibitor of ER-Golgi protein transport and has a high affinity for binding to Cytochrome C oxidase. In bullfrog sympathetic ganglia experiments, Carbonyl Cyanide m-Chlorophenylhydrazone increased the spontaneous release of luteinizing hormone-releasing hormone, with a strong dependence on firing frequency. Furthermore, studies suggest that Carbonyl Cyanide m-Chlorophenylhydrazone acts as a proton conductor, potentially influencing E. coli cell viability in the presence of glucose.