Date published: 2025-12-5

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CD8 Antibodies

Santa Cruz Biotechnology features a diverse variety of CD8 Antibodies, essential tools for researchers studying T cell biology and immune responses. Monoclonal CD8 Antibodies perform effectively in various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CD8 is a glycoprotein found on the surface of cytotoxic T cells, playing a crucial role in the immune system by recognizing and eliminating infected or cancerous cells. The CD8 molecule is vital for T cell activation and function, making CD8 monoclonal antibodies instrumental for studies related to cancer immunotherapy, infectious diseases, and autoimmune disorders. Understanding CD8's role in immune responses can provide insights into therapeutic strategies and disease mechanisms. CD8 monoclonal antibodies enable precise detection and analysis of cytotoxic T cell populations in various experimental settings. Research utilizing CD8 monoclonal antibodies has contributed significantly to understanding cellular immunity and developing targeted therapies. Santa Cruz Biotechnology monoclonal CD8 antibodies support researchers worldwide in advancing scientific knowledge and developing innovative therapeutic approaches in immunology.

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CD8 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CD8 Antibody (32-M4)

sc-1177mouse IgG2a κ(h)WB, IP, IF, FCMm, r, h
30
(11)

CD8 Antibody (2.43)

sc-18860rat IgG2bFL (m)IF, FCMm
13
(6)

CD8 Antibody (UCH-T4)

sc-1181mouse IgG2a κ(h)IP, IF, IHC(P), FCMh
18
(8)

CD8 Antibody (MCD8)

sc-51735mouse IgG1(h)IF, IHC(P), FCMh
2
(2)

CD8 Antibody (5F10)

sc-70794mouse IgG1(h)IF, IHC(P), FCMh
4
(2)

CD8-α Antibody (D-9)

sc-7970mouse IgG2a κ22-182 (h)WB, IP, IF, IHC(P), ELISAm, r, h
44
(18)

CD8-α Antibody (OX8)

sc-53063mouse IgG1 κ(r)WB, IP, IF, IHC(P), FCMm, r
7
(3)

CD8-α Antibody (53-6.7)

sc-18913rat IgG2a(m)IP, IF, IHC(P), FCMm
21
(7)

CD8-α Antibody (6A242)

sc-70802mouse IgG1 κ(r)WB, IP, IF, IHC(P), FCMm, r
6
(2)

CD8-α Antibody (C8/144B)

sc-53212mouse IgG1 κC-Terminal (h)WB, IP, IF, IHC(P)h
13
(3)

CD8-α Antibody (0.N.66)

sc-70791mouse IgG1 κC-Terminal (h)WB, IP, IF, IHC(P)m, r, h

new

(1)

CD8-α Antibody (KT15)

sc-53473rat IgG2aFL (m)IF, FCMm
2
(1)

CD8-β Antibody (F-5)

sc-25277mouse IgG2a κ22-170 (h)WB, IP, IF, IHC(P), ELISAh
6
(7)

CD8-β Antibody (5F2)

sc-19994mouse IgG1 κinternal (r)WB, IP, IF, IHC(P), FCMh
7
(5)

CD8-β Antibody (H35-17.2)

sc-20041rat IgG2bFL (m)IP, IF, IHC(P), FCMm
5
(4)

CD8-β Antibody (53-5.8)

sc-18915rat IgG1FL (m)IP, IF, FCMm

new

(1)

CD8 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD8-α CRISPR/Cas9 KO Plasmid (h)

sc-400372hGene KnockoutGFP0
(0)

CD8-α Double Nickase Plasmid (h)

sc-400372-NIChGene KnockoutPuromycin0
(0)

CD8-α Double Nickase Plasmid (h2)

sc-400372-NIC-2hGene KnockoutPuromycin0
(0)

CD8-α CRISPR/Cas9 KO Plasmid (m)

sc-419576mGene KnockoutGFP0
(0)

CD8-α Double Nickase Plasmid (m)

sc-419576-NICmGene KnockoutPuromycin0
(0)

CD8-α Double Nickase Plasmid (m2)

sc-419576-NIC-2mGene KnockoutPuromycin0
(0)

CD8-β CRISPR/Cas9 KO Plasmid (h)

sc-400950hGene KnockoutGFP0
(0)

CD8-β CRISPR/Cas9 KO Plasmid (h2)

sc-400950-KO-2hGene KnockoutGFP0
(0)

CD8-β HDR Plasmid (h2)

sc-400950-HDR-2hHomology Directed RepairPuromycin0
(0)

CD8-β Double Nickase Plasmid (h)

sc-400950-NIChGene KnockoutPuromycin0
(0)

CD8-β Double Nickase Plasmid (h2)

sc-400950-NIC-2hGene KnockoutPuromycin0
(0)

CD8-β CRISPR/Cas9 KO Plasmid (m)

sc-419577mGene KnockoutGFP0
(0)

CD8-β Double Nickase Plasmid (m)

sc-419577-NICmGene KnockoutPuromycin0
(0)

CD8-β Double Nickase Plasmid (m2)

sc-419577-NIC-2mGene KnockoutPuromycin0
(0)

CD8 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD8-α CRISPR Activation Plasmid (h)

sc-400372-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD8-α CRISPR Activation Plasmid (h2)

sc-400372-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD8-α Lentiviral Activation Particles (h)

sc-400372-LAChGene ActivationPuro, Blast, Hygro0
(0)

CD8-α Lentiviral Activation Particles (h2)

sc-400372-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CD8-α CRISPR Activation Plasmid (m)

sc-419576-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CD8-α CRISPR Activation Plasmid (m2)

sc-419576-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CD8-α Lentiviral Activation Particles (m)

sc-419576-LACmGene ActivationPuro, Blast, Hygro0
(0)

CD8-α Lentiviral Activation Particles (m2)

sc-419576-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CD8-β CRISPR Activation Plasmid (h)

sc-400950-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD8-β CRISPR Activation Plasmid (h2)

sc-400950-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD8-β Lentiviral Activation Particles (h)

sc-400950-LAChGene ActivationPuro, Blast, Hygro0
(0)

CD8-β Lentiviral Activation Particles (h2)

sc-400950-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CD8-β CRISPR Activation Plasmid (m)

sc-419577-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CD8-β CRISPR Activation Plasmid (m2)

sc-419577-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CD8-β Lentiviral Activation Particles (m)

sc-419577-LACmGene ActivationPuro, Blast, Hygro0
(0)

CD8-β Lentiviral Activation Particles (m2)

sc-419577-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CD8 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD8-α siRNA (h)

sc-29247hGene SilencingN/A
1
(0)

CD8-α siRNA (h2)

sc-35028hGene SilencingN/A0
(0)

CD8-α shRNA Plasmid (h)

sc-29247-SHhGene SilencingPuromycin
1
(0)

CD8-α shRNA Plasmid (h2)

sc-35028-SHhGene SilencingPuromycin0
(0)

CD8-α shRNA (h) Lentiviral Particles

sc-29247-VhGene SilencingPuromycin
1
(0)

CD8-α shRNA (h2) Lentiviral Particles

sc-35028-VhGene SilencingPuromycin0
(0)

CD8-α siRNA (m)

sc-43677mGene SilencingN/A0
(0)

CD8-α shRNA Plasmid (m)

sc-43677-SHmGene SilencingPuromycin0
(0)

CD8-α shRNA (m) Lentiviral Particles

sc-43677-VmGene SilencingPuromycin0
(0)

CD8-β siRNA (h)

sc-35029hGene SilencingN/A0
(0)

CD8-β shRNA Plasmid (h)

sc-35029-SHhGene SilencingPuromycin0
(0)

CD8-β shRNA (h) Lentiviral Particles

sc-35029-VhGene SilencingPuromycin0
(0)

CD8-β siRNA (m)

sc-42757mGene SilencingN/A0
(0)

CD8-β shRNA Plasmid (m)

sc-42757-SHmGene SilencingPuromycin0
(0)

CD8-β shRNA (m) Lentiviral Particles

sc-42757-VmGene SilencingPuromycin0
(0)