
CD8-α Antibody (6A242) is a mouse monoclonal IgG1 kappa light chain antibody raised against thymocyte membrane glycoproteins of rat origin, designed for the detection of CD8-α in mouse and rat samples via western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD8-α, also known as CD8A, Leu2, or p32, is a cell surface glycoprotein predominantly expressed on cytotoxic T lymphocytes and some natural killer cells, forming either homodimers (αα) or heterodimers (αβ) with CD8-β. CD8-α plays a crucial role in the immune system by binding to major histocompatibility complex (MHC) class I molecules on antigen-presenting cells, thereby enhancing antigen recognition by the T cell receptor (TCR) and strengthening T cell-antigen presenting cell interactions. This function is essential for the activation and cytotoxic response of CD8+ T cells against intracellular pathogens and tumor cells. CD8-α is vital for T cell development, selection, and peripheral immune responses, making CD8-α a significant marker in immunological research and diagnostics. Anti-CD8-α antibody (6A242) is a valuable tool for studying T cell-mediated immunity and for the identification and characterization of CD8+ T cell populations in various biological samples.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD8-α Antibody (6A242) | sc-70802 | 200 µg/ml | $322.00 | |||
CD8-α Antibody (6A242): m-IgG Fc BP-HRP Bundle | sc-539312 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD8-α Antibody (6A242): m-IgG1 BP-HRP Bundle | sc-541401 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD8-α Antibody (6A242) FITC | sc-70802 FITC | 200 µg/ml | $336.00 | |||
CD8-α Antibody (6A242) L | sc-70802 L | 200 µg/0.1 ml | $322.00 | |||
CD8-α Antibody (6A242) PE | sc-70802 PE | 200 µg/ml | $349.00 |