ALDH1B1 activators belong to a specialized class of chemical compounds known for their ability to modulate the activity of Aldehyde Dehydrogenase 1B1 (ALDH1B1), an enzyme that plays a crucial role in the metabolism of aldehydes within cells. ALDH1B1 is a member of the aldehyde dehydrogenase enzyme superfamily, responsible for the oxidation of a variety of aldehydes to their corresponding carboxylic acids, particularly in the context of cellular detoxification and metabolism. These activators are meticulously designed to interact with ALDH1B1, potentially influencing its enzymatic function and affecting downstream cellular responses related to aldehyde metabolism. At the molecular level, the mechanisms through which ALDH1B1 activators exert their effects can be complex, often involving binding to specific regions of the enzyme or modulating its catalytic activity.
Research on ALDH1B1 activators is instrumental in advancing our understanding of cellular metabolism and detoxification processes, particularly those related to aldehyde compounds. Scientists in this field primarily focus on elucidating the precise molecular mechanisms by which these compounds impact ALDH1B1's function and their downstream effects on aldehyde detoxification and metabolism. Understanding the role of ALDH1B1 activators contributes to our broader knowledge of cell biology and the intricate metabolic pathways that maintain cellular homeostasis. Moreover, these compounds serve as valuable tools for researchers seeking to investigate the molecular basis of aldehyde metabolism and its implications in various physiological and pathological contexts, ultimately deepening our understanding of cellular regulation and metabolic dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Known to modulate the expression of various ALDH isoforms due to its role in cellular differentiation. | ||||||
4-Hydroxynonenal | 75899-68-2 | sc-202019 sc-202019A sc-202019B | 1 mg 10 mg 50 mg | $118.00 $655.00 $2774.00 | 25 | |
Aldehyde product of lipid peroxidation; might induce ALDH1B1 as part of the detoxification process. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
ALDH inhibitor; might indirectly affect ALDH1B1 expression as a compensatory mechanism. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Known to upregulate detoxifying enzymes; potential influence on ALDH1B1. | ||||||
Diallyl sulfide | 592-88-1 | sc-204718 sc-204718A | 25 g 100 g | $42.00 $106.00 | 3 | |
Modulates various detoxification pathways; might influence ALDH1B1. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor; might modulate ALDH1B1 expression epigenetically. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase inhibitor; potential epigenetic modulation of ALDH1B1 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences multiple cellular pathways; might indirectly modulate ALDH1B1 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates various cellular pathways; potential effects on ALDH1B1. | ||||||