Diallyl sulfide Diallyl sulfide is an anticarcinogenic thioester compound isolated from garlic.

Diallyl sulfide (CAS 592-88-1)

Diallyl sulfide | CAS 592-88-1 is rated 5.0 out of 5 by 1.
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Alternate Names: Allyl sulfide; garlic oil
Application: Diallyl sulfide is an anticarcinogenic thioester compound isolated from garlic
CAS Number: 592-88-1
Purity: ≥95%
Molecular Weight: 114.21
Molecular Formula: C6H10S
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Diallyl sulfide is a modulator of drug metabolizing enzyme P450 system and inducer of the phase II detoxifying enzyme GST. Diallyl sulfide is also an inhibitor of CYP2E1 and believed to prevent chemically-induced carcinogenesis in many tissues.


References

Yang CS, Chhabra S, Hong JY, Smith TJ. J Nutr. 131:1041S-5S (2001). Wargovich MJ, Imada O, Stephens LC. Cancer Lett. 64:39-42 (1992). Srivastava SK, Hu X, Zaren HA et al. Cancer Lett. 118:61-67 (1997).

Physical State :
Liquid
Solubility :
Soluble in alcohol, chloroform, ether, and carbon tetrachloride. Insoluble in water.
Storage :
Store at 4° C
Melting Point :
-83° C (lit.)
Boiling Point :
138° C (lit.)
Density :
0.89 g/mL at 25° C
Refractive Index :
n20D 1.49 (lit.)
IC50 :
ANKTM1: EC5050 = 254 µM (human); MDCK: IC50 = 3.26 mM (dog)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
BC4900000
PubChem CID :
11617
Merck Index :
14: 297
MDL Number :
MFCD00008658
EC Number :
209-775-1
Beilstein Registry :
1736016
SMILES :
C=CCSCC=C

Download SDS (MSDS)

Certificate of Analysis

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Diallyl sulfide (CAS 592-88-1)  Product Citations

See how others have used Diallyl sulfide (CAS 592-88-1). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 26567798  Martinez-Gil, N. et al. 2015. Investigative ophthalmology & visual science. 56: 6855-63.

PMID: # 32825644  Antioxidants (Basel).

Citations 1 to 2 of 2 total

Is this product soluble in water?

Asked by: hawkeye11
Thank you for you question. Diallyl sulfide, sc-204718, is insoluble in water. It is miscible in ethyl alcohol and diethyl ether.
Answered by: TechService7
Date published: 2016-12-20
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Rated 5 out of 5 by from Abdel Abdel-Daim, MM. et al. (PubMed 26199917) investigated the protective effects of Diallyl sulfide and curcumin separately against thallium-induced toxicity in rats. Found that pretreatment with Diallyl sulfide or curcumin effectively reduced thallium-induced liver toxicity. -SCBT Publication Review
Date published: 2015-06-19
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