Date published: 2026-4-25

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IRAK-1 Antibodies

Santa Cruz Biotechnology features a diverse variety of IRAK-1 monoclonal antibodies for multiple research applications. IRAK-1 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Interleukin-1 receptor-associated kinase 1 (IRAK-1) plays a crucial role in the signaling pathways of the immune response, particularly in mediating the effects of pro-inflammatory cytokines. IRAK-1 is essential for the activation of downstream signaling cascades that lead to the production of inflammatory mediators, making it a key player in both innate and adaptive immunity. Understanding IRAK-1 function is vital for elucidating mechanisms of various diseases, including autoimmune disorders and cancer. IRAK-1 research continues to reveal new insights into cellular signaling pathways and their regulation. Investigating IRAK-1 expression patterns helps identify potential therapeutic targets for inflammatory conditions. Research using IRAK-1 monoclonal antibodies has advanced our understanding of immune system regulation and disease progression. Santa Cruz Biotechnology monoclonal antibodies for IRAK-1 support researchers worldwide in advancing scientific knowledge of immune system function and disease mechanisms.

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IRAK-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IRAK-1 Antibody (F-4)

sc-5288mouse IgG1 κ440-712 (h)WB, IP, IF, IHC(P), ELISAm, r, h
79
(14)

IRAK-1 Antibody (C-2)

sc-5287mouse IgG2a κ440-712 (h)WB, IP, IF, IHC(P), ELISAh
8
(6)

IRAK-1 Antibody (B-5)

sc-55530mouse IgG2b κ440-712 (h)WB, IP, IF, ELISAh
6
(6)

IRAK-1 Antibody (B-8)

sc-515499mouse IgG2a692-712 (h)WB, IP, IF, ELISAh

new

(2)

IRAK-1 Antibody (E-5)

sc-515512mouse IgG1689-712 (h)WB, IP, IF, ELISAm, r, h
1
(2)

IRAK-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRAK-1 CRISPR/Cas9 KO Plasmid (h)

sc-400264hGene KnockoutGFP
1
(0)

IRAK-1 HDR Plasmid (h)

sc-400264-HDRhHomology Directed RepairPuromycin
1
(0)

IRAK-1 Double Nickase Plasmid (h)

sc-400264-NIChGene KnockoutPuromycin
1
(0)

IRAK-1 Double Nickase Plasmid (h2)

sc-400264-NIC-2hGene KnockoutPuromycin
1
(0)

IRAK-1 CRISPR/Cas9 KO Plasmid (m)

sc-421100mGene KnockoutGFP0
(0)

IRAK-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRAK-1 CRISPR Activation Plasmid (h)

sc-400264-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-1 CRISPR Activation Plasmid (h2)

sc-400264-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-1 CRISPR Activation Plasmid (m)

sc-421100-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRAK-1 siRNA (h)

sc-35704hGene SilencingN/A
7
(0)

IRAK-1 shRNA Plasmid (h)

sc-35704-SHhGene SilencingPuromycin
7
(0)

IRAK-1 shRNA (h) Lentiviral Particles

sc-35704-VhGene SilencingPuromycin
7
(0)

IRAK-1 siRNA (m)

sc-35705mGene SilencingN/A
6
(0)

IRAK-1 shRNA Plasmid (m)

sc-35705-SHmGene SilencingPuromycin
6
(0)

IRAK-1 shRNA (m) Lentiviral Particles

sc-35705-VmGene SilencingPuromycin
6
(0)

IRAK-1 siRNA (r)

sc-270326rGene SilencingN/A
1
(0)

IRAK-1 shRNA Plasmid (r)

sc-270326-SHrGene SilencingPuromycin
1
(0)

IRAK-1 shRNA (r) Lentiviral Particles

sc-270326-VrGene SilencingPuromycin
1
(0)