Date published: 2026-1-20

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IRAK-4 Antibodies

Santa Cruz Biotechnology delivers a wide array of IRAK-4 monoclonal antibodies for research focused on understanding IRAK-4's role in various biological processes. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IRAK-4, or Interleukin-1 receptor-associated kinase 4, is a critical component of the innate immune response, playing a pivotal role in the signaling pathways activated by pro-inflammatory cytokines. IRAK-4 is essential for the activation of downstream signaling molecules that lead to the production of inflammatory mediators, making it a key player in the regulation of immune responses. Dysregulation of IRAK-4 has been implicated in various inflammatory diseases and conditions, highlighting its importance as a therapeutic target. Research using IRAK-4 monoclonal antibodies can reveal new insights into immune system regulation and disease mechanisms. Studying IRAK-4 signaling pathways helps advance understanding of inflammatory conditions and potential treatments. IRAK-4 monoclonal antibodies enable detailed examination of immune response mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific knowledge of immune system function and regulation.

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IRAK-4 Antibodies

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IRAK-4 Antibody (G-2)

sc-374349mouse IgG2a κ1-100 (h)WB, IP, IF, IHC(P), ELISAh
3
(9)

IRAK-4 Antibody (5-RY38)

sc-134368mouse IgG1 κ1-130 (h)WB, IP, ELISAh
1
(1)

IRAK-4 CRISPR Knockout, HDR and Double Nickase Plasmids

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IRAK-4 CRISPR/Cas9 KO Plasmid (h)

sc-416405hGene KnockoutGFP
1
(0)

IRAK-4 HDR Plasmid (h)

sc-416405-HDRhHomology Directed RepairPuromycin
1
(0)

IRAK-4 Double Nickase Plasmid (m)

sc-435222-NICmGene KnockoutPuromycin0
(0)

IRAK-4 Double Nickase Plasmid (m2)

sc-435222-NIC-2mGene KnockoutPuromycin0
(0)

IRAK-4 CRISPR Activation Products

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IRAK-4 CRISPR Activation Plasmid (h)

sc-416405-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-4 CRISPR Activation Plasmid (h2)

sc-416405-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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IRAK-4 siRNA (h)

sc-45400hGene SilencingN/A
1
(0)

IRAK-4 shRNA Plasmid (h)

sc-45400-SHhGene SilencingPuromycin
1
(0)

IRAK-4 shRNA (h) Lentiviral Particles

sc-45400-VhGene SilencingPuromycin
1
(0)

IRAK-4 siRNA (m)

sc-45401mGene SilencingN/A
3
(0)

IRAK-4 shRNA Plasmid (m)

sc-45401-SHmGene SilencingPuromycin
3
(0)

IRAK-4 shRNA (m) Lentiviral Particles

sc-45401-VmGene SilencingPuromycin
3
(0)