CD92 Inhibitors
CD92 inhibitors are a class of chemical compounds specifically designed to target and modulate the activity of the CD92 protein, also known as SLC44A1. CD92 is a member of the solute carrier family 44 (SLC44) and is involved in the transport of organic cations across cellular membranes. This protein plays a vital role in the regulation of cellular uptake and efflux of various molecules, including small organic cations and larger substrates. CD92 inhibitors are primarily utilized in molecular and cellular biology research to investigate the functional properties and regulatory mechanisms associated with this protein.
The development of CD92 inhibitors typically involves a combination of biochemical, biophysical, and structural approaches aimed at identifying or designing molecules that can selectively interact with CD92 and modulate its transport activity. By inhibiting CD92, these compounds can disrupt the transport of organic cations and other substrates mediated by this protein. Researchers use CD92 inhibitors to explore the intricate roles played by CD92 in cellular uptake and efflux processes, including its impact on cellular metabolism and homeostasis. Furthermore, these inhibitors serve as valuable tools for dissecting the broader network of cellular pathways involving organic cation transporters, contributing to our understanding of fundamental cell biology mechanisms and providing insights into avenues for further scientific inquiry.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide is known to inhibit the transcription of various genes by affecting RNA polymerase II activity, potentially reducing the expression of SLC44A1. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine can incorporate into DNA and RNA and cause demethylation of DNA, which may lead to an alteration in gene expression patterns, possibly affecting SLC44A1. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Similar to 5-Azacytidine, Decitabine is a DNA methyltransferase inhibitor, potentially causing hypomethylation of gene promoters and affecting gene expression, including SLC44A1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor, which can change chromatin structure and gene expression, potentially influencing SLC44A1 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat, another histone deacetylase inhibitor, may similarly affect chromatin structure and alter gene expression profiles, including that of SLC44A1. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram can modify the activity of various transcription factors and other proteins through its aldehyde dehydrogenase inhibitory action, which might indirectly affect SLC44A1 expression. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
BIX-01294 is a histone methyltransferase inhibitor that could alter epigenetic regulation and potentially downregulate the expression of genes like SLC44A1. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
RG108 is a non-nucleoside DNA methyltransferase inhibitor; by preventing DNA methylation, it may impact gene expression, including that of SLC44A1. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
C646 is a selective p300/CREB-binding protein histone acetyltransferase inhibitor, potentially altering gene expression by affecting histone modification states, which could include SLC44A1. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
Anacardic acid inhibits histone acetyltransferase activities, potentially affecting transcription and possibly reducing SLC44A1 expression. | ||||||