Solute Carrier Family 44 Member 1 (SLC44A1), also known as CD92, is a transmembrane protein that belongs to the solute carrier family, a diverse group of transport proteins primarily responsible for the movement of various molecules across biological membranes. SLC44A1 Activators, in the context of cellular and molecular biology, refer to compounds or mechanisms that modulate the activity or function of the SLC44A1 protein. SLC44A1 is a member of the choline transporter family, and its primary role in the cell is to facilitate the transport of choline, an essential nutrient and precursor for various membrane phospholipids and the neurotransmitter acetylcholine.
SLC44A1 Activators can act through various mechanisms to regulate the activity of this transporter. These activators may enhance the expression of SLC44A1 on the cell membrane, increase its transport capacity for choline, or modulate its affinity for choline molecules. Additionally, they may impact the intracellular signaling pathways that regulate SLC44A1 activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin is known to activate CD92 (Solute Carrier Family 44 Member 1), increasing its transport function. It can directly interact with CD92 and be taken up into cells via this transporter. | ||||||
Tetrabenazine | 58-46-8 | sc-204338 sc-204338A | 10 mg 50 mg | $165.00 $707.00 | ||
Tetrabenazine is another organic cation that can be transported by CD92 (Solute Carrier Family 44 Member 1), leading to its cellular uptake and activation. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine is an endogenous organic cation and a neurotransmitter. While it may not be a primary substrate of CD92, its presence and transport can indirectly activate CD92 and affect cellular homeostasis and neural signaling. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $102.00 | 3 | |
Quinidine can modulate the activity of various transporters, including CD92 (Solute Carrier Family 44 Member 1). It may influence the activation and transport function of CD92. | ||||||
Probenecid | 57-66-9 | sc-202773 sc-202773A sc-202773B sc-202773C | 1 g 5 g 25 g 100 g | $27.00 $38.00 $98.00 $272.00 | 28 | |
Probenecid is primarily known as an inhibitor of organic anion transporters (OATs). It may also affect CD92 (Solute Carrier Family 44 Member 1), although its mechanism of action on CD92 may be less direct. | ||||||
Cimetidine | 51481-61-9 | sc-202996 sc-202996A | 5 g 10 g | $62.00 $86.00 | 1 | |
Cimetidine can interact with CD92 (Solute Carrier Family 44 Member 1), potentially inhibiting or activating its activity. | ||||||
Paraquat chloride | 1910-42-5 | sc-257968 | 250 mg | $149.00 | 7 | |
Paraquat is a toxic herbicide that is transported by CD92 (Solute Carrier Family 44 Member 1), leading to its cellular uptake and activation. Its transport by CD92 can lead to its cellular uptake and toxicity. | ||||||