Date published: 2026-5-15

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TSC-22 D2 Inhibitors

Tsc-22, or transforming growth factor-β-stimulated clone 22, is a family of proteins that play pivotal roles in various cellular processes, including cell differentiation, proliferation, and immune responses. Tsc-22 D2 inhibitors are a specific class of chemical compounds designed to modulate the activity of the Tsc-22 D2 isoform. Tsc-22 D2, also known as TSC22 domain family protein 2, is a transcriptional regulator involved in numerous cellular pathways. These inhibitors are designed to target the protein's activity and finely tune its functions within the cell.

The Tsc-22 D2 inhibitors typically function by binding to specific sites on the Tsc-22 D2 protein, altering its conformation, and subsequently influencing its transcriptional regulatory activity. By doing so, they can indirectly impact downstream gene expression and cellular processes that are under the control of Tsc-22 D2. These inhibitors have been developed to explore the intricacies of cellular signaling pathways and to elucidate the specific roles played by Tsc-22 D2 in various biological contexts. Researchers utilize these compounds as valuable tools in molecular biology and cellular studies to better understand the fundamental processes governed by Tsc-22 D2 and its implications in diseases and normal physiological functions. Overall, Tsc-22 D2 inhibitors serve as indispensable components in the toolkit of scientists seeking to unravel the complexities of intracellular signaling and gene regulation.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This compound can cause DNA demethylation, potentially leading to altered gene expression patterns and reduced TSC-22 D2 expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, it can change chromatin structure and potentially decrease TSC-22 D2 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

It can modulate gene expression during cell differentiation and may downregulate TSC-22 D2 in certain contexts.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

This agent can cause DNA damage and affect gene expression, potentially leading to decreased TSC-22 D2 levels.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

As an mTOR inhibitor, it can alter cellular growth and proliferation pathways, potentially impacting TSC-22 D2 expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

This natural compound has anti-inflammatory properties and can modulate various cellular signaling pathways, potentially leading to reduced TSC-22 D2 expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Known for its antioxidant properties, it may influence gene expression and reduce TSC-22 D2 levels.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

This compound can induce detoxification enzymes and potentially downregulate TSC-22 D2.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

The main catechin in green tea, it has anti-inflammatory effects and may influence TSC-22 D2 expression.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

As a flavonoid with antioxidant properties, it may modulate signaling pathways and decrease TSC-22 D2 levels.