Tsc-22, or transforming growth factor-β-stimulated clone 22, is a family of proteins that play pivotal roles in various cellular processes, including cell differentiation, proliferation, and immune responses. Tsc-22 D2 inhibitors are a specific class of chemical compounds designed to modulate the activity of the Tsc-22 D2 isoform. Tsc-22 D2, also known as TSC22 domain family protein 2, is a transcriptional regulator involved in numerous cellular pathways. These inhibitors are designed to target the protein's activity and finely tune its functions within the cell.
The Tsc-22 D2 inhibitors typically function by binding to specific sites on the Tsc-22 D2 protein, altering its conformation, and subsequently influencing its transcriptional regulatory activity. By doing so, they can indirectly impact downstream gene expression and cellular processes that are under the control of Tsc-22 D2. These inhibitors have been developed to explore the intricacies of cellular signaling pathways and to elucidate the specific roles played by Tsc-22 D2 in various biological contexts. Researchers utilize these compounds as valuable tools in molecular biology and cellular studies to better understand the fundamental processes governed by Tsc-22 D2 and its implications in diseases and normal physiological functions. Overall, Tsc-22 D2 inhibitors serve as indispensable components in the toolkit of scientists seeking to unravel the complexities of intracellular signaling and gene regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound can cause DNA demethylation, potentially leading to altered gene expression patterns and reduced TSC-22 D2 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, it can change chromatin structure and potentially decrease TSC-22 D2 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
It can modulate gene expression during cell differentiation and may downregulate TSC-22 D2 in certain contexts. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
This agent can cause DNA damage and affect gene expression, potentially leading to decreased TSC-22 D2 levels. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
As an mTOR inhibitor, it can alter cellular growth and proliferation pathways, potentially impacting TSC-22 D2 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
This natural compound has anti-inflammatory properties and can modulate various cellular signaling pathways, potentially leading to reduced TSC-22 D2 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Known for its antioxidant properties, it may influence gene expression and reduce TSC-22 D2 levels. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
This compound can induce detoxification enzymes and potentially downregulate TSC-22 D2. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
The main catechin in green tea, it has anti-inflammatory effects and may influence TSC-22 D2 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
As a flavonoid with antioxidant properties, it may modulate signaling pathways and decrease TSC-22 D2 levels. | ||||||