Date published: 2026-5-15

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TSC-22 D2 Inhibitors

Tsc-22, or transforming growth factor-β-stimulated clone 22, is a family of proteins that play pivotal roles in various cellular processes, including cell differentiation, proliferation, and immune responses. Tsc-22 D2 inhibitors are a specific class of chemical compounds designed to modulate the activity of the Tsc-22 D2 isoform. Tsc-22 D2, also known as TSC22 domain family protein 2, is a transcriptional regulator involved in numerous cellular pathways. These inhibitors are designed to target the protein's activity and finely tune its functions within the cell.

The Tsc-22 D2 inhibitors typically function by binding to specific sites on the Tsc-22 D2 protein, altering its conformation, and subsequently influencing its transcriptional regulatory activity. By doing so, they can indirectly impact downstream gene expression and cellular processes that are under the control of Tsc-22 D2. These inhibitors have been developed to explore the intricacies of cellular signaling pathways and to elucidate the specific roles played by Tsc-22 D2 in various biological contexts. Researchers utilize these compounds as valuable tools in molecular biology and cellular studies to better understand the fundamental processes governed by Tsc-22 D2 and its implications in diseases and normal physiological functions. Overall, Tsc-22 D2 inhibitors serve as indispensable components in the toolkit of scientists seeking to unravel the complexities of intracellular signaling and gene regulation.

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Items 11 to 12 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

This PI3K inhibitor can disrupt AKT signaling, potentially leading to altered TSC-22 D2 expression.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

Primarily used for type 2 diabetes, it can also affect cellular metabolism and potentially reduce TSC-22 D2 expression.