Date published: 2026-5-24

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Topo II α Antibodies

Santa Cruz Biotechnology delivers a wide array of Topo II α monoclonal antibodies for research focused on understanding this critical enzyme. Topo II α Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Topo II α, or topoisomerase II alpha, is essential for DNA replication and cell division, as it helps manage DNA supercoiling and entanglements during these processes. Its proper function is crucial for maintaining genomic stability, and dysregulation of Topo II α has been implicated in various cancers, making it a significant target for therapeutic intervention. Understanding the dynamics of Topo II α can provide insights into cellular processes and potential pathways for drug development. Researchers worldwide rely on Topo II α monoclonal antibodies to investigate DNA topology and its role in cell cycle regulation. Advanced research with Topo II α monoclonal antibodies has revealed important mechanisms in chromosome segregation and DNA organization. The high specificity of Topo II α monoclonal antibodies enables precise detection and analysis of this enzyme in various experimental settings. Santa Cruz Biotechnology monoclonal antibodies for Topo II α continue to advance scientific understanding of cellular processes and potential therapeutic strategies in cancer research.

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Topo II α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Topo IIα Antibody (F-12)

sc-365916mouse IgG1 κ1511-1530 (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(13)

Topo IIα Antibody (G-6)

sc-166934mouse IgG2b κ1301-1531 (h)WB, IP, IF, IHC(P), ELISAh
5
(8)

Topo IIα Antibody (A-8)

sc-165986mouse IgG1 κ1301-1531 (h)WB, IP, IF, ELISAh
6
(2)

Topo IIα Antibody (B-6)

sc-365918mouse IgG2b κ1483-1517 (h)WB, IP, IF, ELISAh
1
(2)

Topo IIα Antibody (E-10)

sc-365799mouse IgM κ1511-1530 (h)WB, IP, IF, ELISAm, r, h
1
(1)

Topo IIα Antibody (E-11)

sc-365917mouse IgG1 κ1483-1517 (h)WB, IP, IF, ELISAh

new

(2)

Topo IIα Antibody (G-9)

sc-166232mouse IgG1 κ1301-1531 (h)WB, IP, IF, ELISAh

new

(2)

Topo II α CRISPR Knockout, HDR and Double Nickase Plasmids

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Topo IIα CRISPR/Cas9 KO Plasmid (h)

sc-400869hGene KnockoutGFP
1
(0)

Topo IIα HDR Plasmid (h)

sc-400869-HDRhHomology Directed RepairPuromycin
1
(0)

Topo IIα CRISPR/Cas9 KO Plasmid (m)

sc-423469mGene KnockoutGFP
1
(0)

Topo IIα HDR Plasmid (m)

sc-423469-HDRmHomology Directed RepairPuromycin
1
(0)

Topo II α CRISPR Activation Products

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Topo IIα CRISPR Activation Plasmid (h)

sc-400869-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Topo IIα CRISPR Activation Plasmid (h2)

sc-400869-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Topo II α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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Topo IIα siRNA (h)

sc-36695hGene SilencingN/A
10
(0)

Topo IIα shRNA Plasmid (h)

sc-36695-SHhGene SilencingPuromycin
10
(0)

Topo IIα shRNA (h) Lentiviral Particles

sc-36695-VhGene SilencingPuromycin
10
(0)

Topo IIα siRNA (m)

sc-36696mGene SilencingN/A0
(0)

Topo IIα shRNA Plasmid (m)

sc-36696-SHmGene SilencingPuromycin0
(0)

Topo IIα shRNA (m) Lentiviral Particles

sc-36696-VmGene SilencingPuromycin0
(0)