Topo I Antibodies

Santa Cruz Biotechnology delivers a wide array of Topo I monoclonal antibodies for advanced research in molecular biology. Topo I Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Topoisomerase I (Topo I) is a crucial enzyme that plays a significant role in DNA replication and transcription by alleviating torsional strain in the DNA helix. Topo I activity is essential for maintaining genomic stability and regulating gene expression, making it a key target in cancer research and therapeutic development. Dysregulation of Topo I has been implicated in various diseases, highlighting its importance in understanding cellular processes and developing targeted treatments. Topo I research has revealed critical insights into DNA topology management and its impact on cellular function. Understanding Topo I mechanisms has led to significant advances in cancer therapy development and DNA repair pathway research. Ongoing studies of Topo I continue to uncover new aspects of genome maintenance and cellular regulation. Santa Cruz Biotechnology monoclonal antibodies for Topo I support researchers worldwide in advancing scientific understanding of DNA dynamics and disease mechanisms.