Topo II Antibodies

Santa Cruz Biotechnology delivers a wide array of Topo II Antibodies for advanced research in molecular biology. Topo II Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Topoisomerase II (Topo II) plays a critical role in DNA replication and transcription by alleviating the torsional strain that occurs ahead of the replication fork. The enzyme maintains genomic stability and serves as a key target in cancer therapy, as inhibition can lead to the selective killing of rapidly dividing cells. Understanding the function and regulation of Topo II is crucial for developing effective treatments for various malignancies. Researchers can explore DNA topology changes during cellular processes such as chromosome condensation and segregation. Advanced visualization techniques using specific markers help track Topo II localization throughout the cell cycle. Investigating Topo II interactions with other nuclear proteins provides valuable information about DNA damage response pathways. Santa Cruz Biotechnology monoclonal antibodies for Topo II research support scientists worldwide in advancing cancer research and therapeutic development.