SLMO2 inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the SLMO2 protein, also known as slowmo homolog 2. SLMO2 is a mitochondrial protein believed to play a role in regulating mitochondrial dynamics, including the processes of mitochondrial fusion and fission. These dynamics are crucial for maintaining mitochondrial integrity, distribution, and function within cells. By influencing mitochondrial morphology and movement, SLMO2 contributes to cellular energy metabolism and overall cellular homeostasis. Inhibitors of SLMO2 are used to study its function by disrupting its normal activity, thereby providing insights into how changes in mitochondrial dynamics affect cellular physiology.
The mechanism of action for SLMO2 inhibitors typically involves binding to specific domains of the SLMO2 protein, preventing it from interacting with other proteins involved in mitochondrial dynamics. This interference can lead to alterations in mitochondrial shape, distribution, and function. By inhibiting SLMO2, researchers can observe changes in processes such as energy production, apoptosis, and the generation of reactive oxygen species. Studying these inhibitors enhances the understanding of the intricate relationship between mitochondrial dynamics and cellular health, highlighting the essential role that proteins like SLMO2 play in maintaining the balance of cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Mdivi-1 inhibits mitochondrial division, potentially altering the lipid homeostasis and function of PDC3B. | ||||||
GW4869 | 6823-69-4 | sc-218578 sc-218578A | 5 mg 25 mg | $203.00 $611.00 | 24 | |
GW4869 disrupts ceramide metabolism that could interfere with intracellular transport, potentially inhibiting PDC3B. | ||||||
Bongkrekic acid | 11076-19-0 | sc-205606 | 100 µg | $400.00 | 10 | |
By blocking the adenine nucleotide translocator, it may disrupt mitochondrial processes linked to PDC3B. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $77.00 $153.00 $240.00 | 8 | |
As an uncoupler of oxidative phosphorylation, CCCP could indirectly inhibit PDC3B by disrupting its mitochondrial context. | ||||||
Ritonavir | 155213-67-5 | sc-208310 | 10 mg | $124.00 | 7 | |
Ritonavir is known to interfere with lipid metabolism, which could hypothetically affect PDC3B. | ||||||
(+)-Etomoxir sodium salt | 828934-41-4 | sc-215009 sc-215009A | 5 mg 25 mg | $151.00 $506.00 | 3 | |
By inhibiting carnitine palmitoyltransferase, etomoxir may inhibit fatty acid transport into mitochondria, affecting PDC3B. | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | $143.00 $510.00 | 2 | |
As an intracellular cholesterol transport inhibitor, U18666A might influence lipid-related functions of PDC3B. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
Fenofibrate activates PPARα, leading to altered lipid metabolism, possibly inhibiting PDC3B. | ||||||
Triacsin C Solution in DMSO | 76896-80-5 | sc-200574 sc-200574A | 100 µg 1 mg | $187.00 $843.00 | 14 | |
This compound inhibits acyl-CoA synthetase, which is crucial for lipid metabolism, potentially inhibiting PDC3B. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
By inhibiting N-linked glycosylation, tunicamycin may disrupt proper folding and function of PDC3B. | ||||||