Date published: 2026-5-6

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PDE CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. PDE gene silencers are available as PDE CRISPR/Cas9 Knockout plasmids and PDE Double Nickase Plasmids. PDE CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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PDE CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDE1A CRISPR/Cas9 KO Plasmid (h)

sc-402409hGene KnockoutGFP0
(0)

PDE1A HDR Plasmid (h)

sc-402409-HDRhHomology Directed RepairPuromycin0
(0)

PDE1B CRISPR/Cas9 KO Plasmid (h)

sc-406446hGene KnockoutGFP0
(0)

PDE1B HDR Plasmid (h)

sc-406446-HDRhHomology Directed RepairPuromycin0
(0)

PDE2A CRISPR/Cas9 KO Plasmid (h)

sc-401957hGene KnockoutGFP0
(0)

PDE2A HDR Plasmid (h)

sc-401957-HDRhHomology Directed RepairPuromycin0
(0)

PDE3A CRISPR/Cas9 KO Plasmid (h)

sc-402183hGene KnockoutGFP0
(0)

PDE3A HDR Plasmid (h)

sc-402183-HDRhHomology Directed RepairPuromycin0
(0)

PDE3A Double Nickase Plasmid (h)

sc-402183-NIChGene KnockoutPuromycin0
(0)

PDE3A Double Nickase Plasmid (h2)

sc-402183-NIC-2hGene KnockoutPuromycin0
(0)

PDE3B CRISPR/Cas9 KO Plasmid (h)

sc-401773hGene KnockoutGFP0
(0)

PDE4B HDR Plasmid (h)

sc-401961-HDRhHomology Directed RepairPuromycin0
(0)

PDE4B CRISPR/Cas9 KO Plasmid (m)

sc-422161mGene KnockoutGFP0
(0)

PDE4B HDR Plasmid (m)

sc-422161-HDRmHomology Directed RepairPuromycin0
(0)

PDE4B Double Nickase Plasmid (m)

sc-422161-NICmGene KnockoutPuromycin0
(0)

PDE4B Double Nickase Plasmid (m2)

sc-422161-NIC-2mGene KnockoutPuromycin0
(0)

PDE4C CRISPR/Cas9 KO Plasmid (h)

sc-404832hGene KnockoutGFP0
(0)

PDE4C HDR Plasmid (h)

sc-404832-HDRhHomology Directed RepairPuromycin0
(0)

PDE4D CRISPR/Cas9 KO Plasmid (h2)

sc-401427-KO-2hGene KnockoutGFP0
(0)

PDE4D HDR Plasmid (h2)

sc-401427-HDR-2hHomology Directed RepairPuromycin0
(0)

PDE5A Double Nickase Plasmid (h)

sc-401627-NIChGene KnockoutPuromycin0
(0)

PDE5A Double Nickase Plasmid (h2)

sc-401627-NIC-2hGene KnockoutPuromycin0
(0)

PDE5A Double Nickase Plasmid (m)

sc-433880-NICmGene KnockoutPuromycin0
(0)

PDE5A Double Nickase Plasmid (m2)

sc-433880-NIC-2mGene KnockoutPuromycin0
(0)

PDE7B CRISPR/Cas9 KO Plasmid (h)

sc-411961hGene KnockoutGFP0
(0)

PDE7B HDR Plasmid (h)

sc-411961-HDRhHomology Directed RepairPuromycin0
(0)

PDE CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDE2A CRISPR Activation Plasmid (h)

sc-401957-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDE2A CRISPR Activation Plasmid (h2)

sc-401957-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDE2A Lentiviral Activation Particles (h)

sc-401957-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDE2A Lentiviral Activation Particles (h2)

sc-401957-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PDE3B CRISPR Activation Plasmid (h)

sc-401773-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDE4B CRISPR Activation Plasmid (m)

sc-422161-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PDE4B Lentiviral Activation Particles (m)

sc-422161-LACmGene ActivationPuro, Blast, Hygro0
(0)

PDE4D CRISPR Activation Plasmid (m)

sc-433646-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

PDE4D CRISPR Activation Plasmid (m2)

sc-433646-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

PDE6β CRISPR Activation Plasmid (m)

sc-422166-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PDE6β Lentiviral Activation Particles (m)

sc-422166-LACmGene ActivationPuro, Blast, Hygro0
(0)

PDE7B CRISPR Activation Plasmid (h)

sc-411961-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDE7B CRISPR Activation Plasmid (h2)

sc-411961-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDE7B Lentiviral Activation Particles (h)

sc-411961-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDE10A CRISPR Activation Plasmid (h)

sc-403981-ACThGene ActivationPuro, Blast, Hygro0
(0)