The term LOC644196 Inhibitors designates a specialized class of chemical compounds meticulously designed to modulate the activity of LOC644196, a molecular target currently under scientific scrutiny. These inhibitors are intricately crafted through principles rooted in medicinal chemistry, with a primary focus on selectively interfering with the normal functions of LOC644196 within cellular processes. The structural features of LOC644196 Inhibitors undergo a rigorous optimization process, often involving computational modeling and structure-activity relationship studies, to refine their molecular configurations for precise binding to the target.
The significance of LOC644196 Inhibitors lies in their potential to disrupt the biochemical activities associated with LOC644196, a molecular entity believed to play a role in various biological pathways. Researchers in this field delve into the three-dimensional structure of LOC644196 and its binding interactions with inhibitors, aiming to unravel the intricate molecular mechanisms underlying inhibition. The study of LOC644196 Inhibitors contributes to a broader understanding of cellular processes, offering insights into the roles played by LOC644196 in diverse biological pathways and expanding our knowledge of the regulatory networks governing cellular activities. This research not only advances our comprehension of the molecular intricacies surrounding LOC644196 but also contributes to the broader scientific understanding of molecular targets and their involvement in fundamental cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate is a folate analog that inhibits dihydrofolate reductase, leading to reduced purine nucleotide synthesis and could indirectly affect PAICS expression. | ||||||
6-Mercaptopurine | 50-44-2 | sc-361087 sc-361087A | 50 mg 100 mg | $71.00 $102.00 | ||
As a purine analog, 6-Mercaptopurine gets incorporated into DNA and RNA, disrupting purine biosynthesis and potentially decreasing PAICS expression. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
This compound inhibits inosine monophosphate dehydrogenase, a key enzyme in the guanine nucleotide synthesis, possibly influencing PAICS levels. | ||||||
Sulfamethoxazole | 723-46-6 | sc-208405 sc-208405A sc-208405B sc-208405C | 10 g 25 g 50 g 100 g | $36.00 $54.00 $68.00 $107.00 | 5 | |
Sulfamethoxazole is a sulfonamide antibiotic that inhibits dihydropteroate synthase, which can lead to decreased purine synthesis and affect PAICS. | ||||||
Azaserine | 115-02-6 | sc-29063 sc-29063A | 50 mg 250 mg | $306.00 $906.00 | 15 | |
Azaserine is a glutamine antagonist that inhibits several glutamine-utilizing enzymes, potentially affecting purine biosynthesis and PAICS expression. | ||||||
Acivicin | 42228-92-2 | sc-200498B sc-200498C sc-200498 sc-200498D | 1 mg 5 mg 10 mg 25 mg | $102.00 $408.00 $642.00 $1275.00 | 10 | |
Acivicin is an inhibitor of glutamine-dependent enzymes and could inhibit the purine biosynthesis pathway, affecting PAICS activity. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-FU is a pyrimidine analog that disrupts nucleotide synthesis. Its metabolites can interfere with purine synthesis, potentially affecting PAICS. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, decreasing the pool of deoxyribonucleotides, which could indirectly affect PAICS expression. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $62.00 $108.00 $210.00 | 1 | |
Ribavirin is a guanosine analog that inhibits inosine monophosphate dehydrogenase, potentially affecting the purine biosynthesis pathway and PAICS levels. | ||||||
Tiazofurin | 60084-10-8 | sc-475805 | 5 mg | $440.00 | ||
Tiazofurin inhibits inosine monophosphate dehydrogenase, which could reduce purine nucleotide biosynthesis and PAICS expression. | ||||||