Date published: 2025-11-28

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Ribavirin (CAS 36791-04-5)

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Alternate Names:
1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
Application:
Ribavirin is a broad spectrum antiviral nucleoside and inhibitor of inosine monophosphate dehydrogenase
CAS Number:
36791-04-5
Purity:
>98%
Molecular Weight:
244.20
Molecular Formula:
C8H12N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ribavirin is a non-interferon-inducing, broad spectrum antiviral nucleoside. Ribavirin is reported to be active against RSV, HIV, HCV, and other infectious agents. The compound′s metabolite, ribavirin-5′-phosphate, inhibits inosine monophosphate (IMP) dehydrogenase.


Ribavirin (CAS 36791-04-5) References

  1. Should ribavirin be used to treat hepatitis C in dialysis patients?  |  Carrion, AF., et al. 2011. Semin Dial. 24: 272-4. PMID: 21480995
  2. Ribavirin efficiently suppresses porcine nidovirus replication.  |  Kim, Y. and Lee, C. 2013. Virus Res. 171: 44-53. PMID: 23108045
  3. Ribavirin: the need for exposure precautions.  |  Mooney, K., et al. 2014. Clin J Oncol Nurs. 18: E93-6. PMID: 25253120
  4. Ribavirin stimulates the immune response of Atlantic salmon.  |  Rivas-Aravena, A., et al. 2015. Vet Immunol Immunopathol. 164: 93-100. PMID: 25631788
  5. Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.  |  Tate, PM., et al. 2019. Cell Rep. 28: 2620-2633.e4. PMID: 31484073
  6. Antiviral activity of ribavirin and favipiravir against human astroviruses.  |  Janowski, AB., et al. 2020. J Clin Virol. 123: 104247. PMID: 31864069
  7. Transport of ribavirin in human myelogenous leukemia cell line K562.  |  Takano, M., et al. 2020. Pharmazie. 75: 329-334. PMID: 32635975
  8. Evaluation of Ribavirin-Poloxamer Microparticles for Improved Intranasal Absorption.  |  Vasa, DM., et al. 2021. Pharmaceutics. 13: PMID: 34452087
  9. Influence of Ribavirin on Mumps Virus Population Diversity.  |  Jurković, M., et al. 2021. Viruses. 13: PMID: 34960805
  10. Toxicity of Ribavirin to Spodoptera litura by Inhibiting the Juvenile Hormone.  |  Li, D., et al. 2022. J Agric Food Chem. 70: 3117-3126. PMID: 35229607
  11. Improved HPLC method for the determination of ribavirin concentration in red blood cells and its application in patients with COVID-19.  |  Liu, L., et al. 2022. Biomed Chromatogr. 36: e5370. PMID: 35297066
  12. Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5.  |  Zhang, Q., et al. 2022. Basic Clin Pharmacol Toxicol. 131: 18-33. PMID: 35470570
  13. Final results from the ribavirin pregnancy registry, 2004-2020.  |  Sinclair, SM., et al. 2022. Birth Defects Res. 114: 1376-1391. PMID: 36305304

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ribavirin, 10 mg

sc-203238
10 mg
$62.00

Ribavirin, 100 mg

sc-203238A
100 mg
$108.00

Ribavirin, 5 g

sc-203238B
5 g
$210.00

In which diluent do you recommend using for the in mice treatment?

Asked by: MECLV
Thank you for your question. It would be helpful if you could call us directly at 800-457-3801 ext.1, allowing for a more interactive discussion of this and other related questions
Answered by: Blake J
Date published: 2021-10-11

Hi, How can I solve the powdered ribavirin ≥ 98% pure? thanks

Asked by: Elaheh
Thank you for your question. Ribavirin (CAS 36791-04-5) sc-203238 is soluble in water (20 mg/ml), DMSO (49 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and alcohol (slightly). For further information please contact our technical service team.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-29
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Rated 5 out of 5 by from ShiShi, F. et al. (PubMed 26317515) found that Ribavirin, a broad spectrum antiviral nucleoside, inhibits the activity of mTOR/eIF4E, ERK/Mnk1/eIF4E signaling pathway and synergizes with tyrosine kinase inhibitor Imatinib to impair Bcr-Abl mediated proliferation and apoptosis in Ph+ leukemia. -SCBT Publication Review
Date published: 2015-01-05
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Ribavirin is rated 5.0 out of 5 by 1.
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