Date published: 2026-3-22

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Sulfamethoxazole (CAS 723-46-6)

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Alternate Names:
4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; 3-(p-Aminobenzenesulfonamido)-5-methylisoxazole; 3-Sulfanilamido-5-methylisoxazole
Application:
Sulfamethoxazole is an inhibitor of the enzyme dihydropteroate synthase
CAS Number:
723-46-6
Molecular Weight:
253.28
Molecular Formula:
C10H11N3O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sulfamethoxazole is a compound that is utilized in research studies for its antibacterial properties, specifically targeting bacterial dihydropteroate synthase involved in folate synthesis. This research is critical for understanding the mechanism of action of antibiotics and the development of bacterial resistance. In environmental microbiology, Sulfamethoxazole is often used to assess the degradation and removal of antibiotic residues in water treatment facilities, as well as their impact on bacterial communities in natural aquatic systems. The compound is also a subject of interest in analytical chemistry for the development of detection methods to monitor its presence in environmental samples.


Sulfamethoxazole (CAS 723-46-6) References

  1. Sorption of sulfamethoxazole onto six types of microplastics.  |  Guo, X., et al. 2019. Chemosphere. 228: 300-308. PMID: 31035168
  2. Biological conversion of sulfamethoxazole in an autotrophic denitrification system.  |  Zhang, L., et al. 2020. Water Res. 185: 116156. PMID: 33086460
  3. Complete decomposition of sulfamethoxazole during an advanced oxidation process in a simple water treatment system.  |  Suzuki, N., et al. 2022. Chemosphere. 287: 132029. PMID: 34474387
  4. Enhanced removal efficiency of sulfamethoxazole by acclimated microalgae: Tolerant mechanism, and transformation products and pathways.  |  Zhang, Y., et al. 2022. Bioresour Technol. 347: 126461. PMID: 34863845
  5. Efficient degradation of sulfamethoxazole under visible light irradiation by polyaniline/copper sulfide composite photocatalyst.  |  Yang, J., et al. 2022. Environ Sci Pollut Res Int. 29: 36502-36511. PMID: 35064877
  6. Effective photocatalytic degradation of sulfamethoxazole using tunable CaCu3Ti4O7 perovskite.  |  Lien, E., et al. 2022. Chemosphere. 294: 133744. PMID: 35093422
  7. Toxic effects and molecular mechanisms of sulfamethoxazole on Scenedesmus obliquus.  |  Xu, D., et al. 2022. Ecotoxicol Environ Saf. 232: 113258. PMID: 35104774
  8. Influence of sulfamethoxazole on anaerobic digestion: Methanogenesis, degradation mechanism and toxicity evolution.  |  Tang, T., et al. 2022. J Hazard Mater. 431: 128540. PMID: 35220120
  9. Sulfamethoxazole removal from mariculture wastewater in moving bed biofilm reactor and insight into the changes of antibiotic and resistance genes.  |  Chen, Y., et al. 2022. Chemosphere. 298: 134327. PMID: 35304219
  10. Sulfamethoxazole induces brain capillaries toxicity in zebrafish by up-regulation of VEGF and chemokine signalling.  |  Xu, Y., et al. 2022. Ecotoxicol Environ Saf. 238: 113620. PMID: 35561544
  11. Anaerobic sulfamethoxazole-degrading bacterial consortia in antibiotic-contaminated wetland sediments identified by DNA-stable isotope probing and metagenomics analysis.  |  Chen, J., et al. 2022. Environ Microbiol. 24: 3751-3763. PMID: 35688651
  12. Biotransformation of sulfamethoxazole by microalgae: Removal efficiency, pathways, and mechanisms.  |  Chu, Y., et al. 2022. Water Res. 221: 118834. PMID: 35839594
  13. Enhanced adsorption performance of sulfamethoxazole and tetracycline in aqueous solutions by MgFe2O4-magnetic biochar.  |  Deng, Y., et al. 2022. Water Sci Technol. 86: 568-583. PMID: 35960837
  14. Sulfamethoxazole Enhances Specific Enzymatic Activities under Aerobic Heterotrophic Conditions: A Metaproteomic Approach.  |  Kennes-Veiga, DM., et al. 2022. Environ Sci Technol. 56: 13152-13159. PMID: 36073795

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sulfamethoxazole, 10 g

sc-208405
10 g
$37.00

Sulfamethoxazole, 25 g

sc-208405A
25 g
$55.00

Sulfamethoxazole, 50 g

sc-208405B
50 g
$69.00

Sulfamethoxazole, 100 g

sc-208405C
100 g
$109.00