Date published: 2025-12-10

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Ku70 Antibodies

Santa Cruz Biotechnology provides a broad selection of Ku70 monoclonal antibodies for research focused on understanding Ku70 protein's role in cellular processes. Ku70 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Ku70 is a vital component of the DNA repair machinery, playing a key role in the non-homologous end joining (NHEJ) pathway, which is essential for maintaining genomic stability. By binding to DNA double-strand breaks, Ku70 facilitates the recruitment of other repair factors, thereby preventing genomic instability and contributing to cellular survival. The significance of Ku70 extends to various biological processes, including immune response and cellular aging. Ku70 monoclonal antibodies enable detailed investigation of DNA repair mechanisms and their impact on cellular health. Understanding Ku70's function has implications for cancer research, aging studies, and immune system regulation. Research utilizing Ku70 monoclonal antibodies from Santa Cruz Biotechnology continues to advance scientific understanding of DNA repair mechanisms and cellular homeostasis.

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Ku70 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Ku70 Antibody (E-5)

sc-17789mouse IgG1 κ302-609 (h)WB, IP, IF, IHC(P), ELISAm, r, h
92
(31)

Ku70 Antibody (A-9)

sc-5309mouse IgG2a κ302-609 (h)WB, IP, IF, IHC(P), FCM, ELISAh
78
(20)

Ku70 Antibody (N3H10)

sc-56129mouse IgG2b κ(h)WB, IP, IF, IHC(P)m, r, h
22
(6)

Ku70 Antibody (3C3.11)

sc-12729mouse IgG1 κFL (h)WB, IP, IFh
10
(4)

Ku70 Antibody (0.N.376)

sc-71470mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
2
(2)

Ku70 Antibody (G-7)

sc-55505mouse IgG1 κ302-609 (h)WB, IP, IF, IHC(P), ELISAh
3
(4)

Ku70 Antibody (H-6)

sc-365766mouse IgG1 κ583-608 (h)WB, IP, IF, ELISAm, r, h
2
(2)

Ku70 Antibody (3F246)

sc-71469mouse IgG2b κ(h)WB, IP, IF, IHC(P)m, r, h
1
(3)

Ku70 Antibody (G-4)

sc-166386mouse IgG2b κ564-595 (m)WB, IP, IF, ELISAm, r, h

new

(1)

Ku70 Antibody (S5C11)

sc-56130mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(3)

Ku70 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ku-70 CRISPR/Cas9 KO Plasmid (h2)

sc-400378-KO-2hGene KnockoutGFP0
(0)

Ku-70 HDR Plasmid (h2)

sc-400378-HDR-2hHomology Directed RepairPuromycin0
(0)

Ku-70 Double Nickase Plasmid (h)

sc-400378-NIChGene KnockoutPuromycin0
(0)

Ku-70 Double Nickase Plasmid (h2)

sc-400378-NIC-2hGene KnockoutPuromycin0
(0)

Ku70 CRISPR/Cas9 KO Plasmid (m)

sc-420441mGene KnockoutGFP0
(0)

Ku70 HDR Plasmid (m)

sc-420441-HDRmHomology Directed RepairPuromycin0
(0)

Ku70 Double Nickase Plasmid (m)

sc-420441-NICmGene KnockoutPuromycin0
(0)

Ku70 Double Nickase Plasmid (m2)

sc-420441-NIC-2mGene KnockoutPuromycin0
(0)

Ku70 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ku-70 CRISPR Activation Plasmid (h)

sc-400378-ACThGene ActivationPuro, Blast, Hygro0
(0)

Ku-70 CRISPR Activation Plasmid (h2)

sc-400378-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Ku-70 Lentiviral Activation Particles (h)

sc-400378-LAChGene ActivationPuro, Blast, Hygro0
(0)

Ku-70 Lentiviral Activation Particles (h2)

sc-400378-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Ku70 CRISPR Activation Plasmid (m)

sc-420441-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Ku70 CRISPR Activation Plasmid (m2)

sc-420441-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Ku70 Lentiviral Activation Particles (m)

sc-420441-LACmGene ActivationPuro, Blast, Hygro0
(0)

Ku70 Lentiviral Activation Particles (m2)

sc-420441-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Ku70 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ku70 siRNA (h)

sc-29383hGene SilencingN/A
11
(0)

Ku70 shRNA Plasmid (h)

sc-29383-SHhGene SilencingPuromycin
11
(0)

Ku70 shRNA (h) Lentiviral Particles

sc-29383-VhGene SilencingPuromycin
11
(0)

Ku70 siRNA (m)

sc-35764mGene SilencingN/A
1
(0)

Ku70 shRNA Plasmid (m)

sc-35764-SHmGene SilencingPuromycin
1
(0)

Ku70 shRNA (m) Lentiviral Particles

sc-35764-VmGene SilencingPuromycin
1
(0)