Ku70 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $62.00 $225.00 $779.00 | 24 | |
Nutlin-3 inhibits Ku70 by disrupting the interaction between Ku70 and Bax, preventing DNA repair and promoting apoptosis. | ||||||
NSC 319726 | 71555-25-4 | sc-477736 | 10 mg | $159.00 | ||
NSC 319726 inhibits Ku70 by interfering with its binding to DNA, leading to impaired DNA repair mechanisms and increased sensitivity to DNA damage. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits Ku70 by targeting the PI3K/Akt signaling pathway, resulting in reduced phosphorylation of Ku70 and impaired DNA repair capacity. | ||||||
KU 60019 | 925701-46-8 | sc-363284 sc-363284A | 10 mg 50 mg | $248.00 $1035.00 | 1 | |
Ku-60019 inhibits Ku70 by blocking its interaction with DNA-PKcs, leading to impaired DNA repair and increased susceptibility to DNA damage-induced cell death. | ||||||
NU 7441 | 503468-95-9 | sc-208107 | 5 mg | $357.00 | 10 | |
NU7441 inhibits Ku70 by targeting the DNA-PK pathway, resulting in decreased recruitment of Ku70 to DNA damage sites and compromised DNA repair mechanisms. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits Ku70 by blocking the PI3K/Akt/mTOR signaling pathway, leading to reduced phosphorylation of Ku70 and attenuation of its DNA repair functions. | ||||||
DNA-PK Inhibitor II | 154447-35-5 | sc-202143 sc-202143A | 10 mg 50 mg | $155.00 $660.00 | 6 | |
DNA-PK Inhibitor II inhibits Ku70 by interfering with the DNA-PK signaling pathway, thereby suppressing the recruitment of Ku70 to DNA damage sites and impairing DNA repair processes. | ||||||
ATM/ATR Kinase Inhibitor Inhibitor | 905973-89-9 | sc-202964 | 5 mg | $106.00 | 8 | |
ATM/ATR Kinase Inhibitor inhibits Ku70 by disrupting its interaction with Bax, leading to inhibition of DNA repair and induction of apoptosis in cancer cells. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
ATM Kinase Inhibitor inhibits Ku70 by targeting the ATM signaling pathway, resulting in impaired DNA repair and increased sensitivity to DNA damage-induced cell death. | ||||||
NU 1025 | 90417-38-2 | sc-203166 | 5 mg | $131.00 | 9 | |
NU1025 inhibits Ku70 by blocking the PARP enzyme, leading to accumulation of DNA damage and inhibition of DNA repair processes mediated by Ku70. | ||||||