Ku70 Antibody (G-7): sc-55505
- Ku70 Antibody (G-7) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 302-609 of Ku70 of human origin
- recommended for detection of Ku70 of human origin by WB, IP, IF, IHC(P) and ELISA
- See Ku70 (E-5): sc-17789 for Ku70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ku70 Antibody (G-7) for WB and IHC(P) applications. These reagents are now offered in bundles with Ku70 Antibody (G-7) (see ordering information below).
Ku70 Antibody (G-7) is a mouse monoclonal IgG1 antibody that detects Ku70 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Ku70 is a crucial component of the Ku protein complex, which is localized in the nucleus and consists of two subunits, Ku70 (p70) and Ku86 (p86), the latter also known as Ku80 or p80. Anti-Ku70 antibody (G-7) plays a vital role in studying DNA repair and maintenance of genomic stability, as Ku70 is involved in the non-homologous end joining (NHEJ) pathway, a primary mechanism for repairing double-strand breaks in DNA. Ku70′s ability to bind to DNA ends is essential for the recruitment of other repair factors, thereby facilitating the repair process and preventing genomic instability, which can lead to cancer and other diseases. Additionally, Ku70 has been implicated in regulating transcription, as Ku70 interacts with various transcription factors and RNA polymerase II, influencing gene expression. Ku70 (G-7) antibody is an invaluable tool for researchers studying DNA repair mechanisms, transcription regulation, and the role of Ku proteins in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ku70 Antibody (G-7) | sc-55505 | 200 µg/ml | $316.00 | |||
Ku70 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-537057 | 200 µg Ab; 10 µg BP | $354.00 | |||
Ku70 Antibody (G-7): m-IgGκ BP-HRP Bundle | sc-534242 | 200 µg Ab; 40 µg BP | $354.00 | |||
Ku70 Antibody (G-7): m-IgG1 BP-HRP Bundle | sc-544979 | 200 µg Ab; 20 µg BP | $354.00 |