Ku70 Antibody (G-4): sc-166386
- Ku70 Antibody (G-4) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 564-595 at the C-terminus of Ku70 of mouse origin
- recommended for detection of Ku70 of mouse, rat and human origin by WB, IP, IF and ELISA
- See Ku70 (E-5): sc-17789 for Ku70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ku70 Antibody (G-4) for WB applications. These reagents are now offered in bundles with Ku70 Antibody (G-4) (see ordering information below).
Ku70 Antibody (G-4) is a mouse monoclonal IgG2b antibody that detects Ku70 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Ku70 is a crucial component of the Ku protein complex, which is localized in the nucleus and consists of two subunits, Ku70 (p70) and Ku86 (p86), the latter also known as Ku80 or p80. Ku70 plays a vital role in DNA repair and maintenance of genomic stability, binding to double-stranded DNA breaks and recruiting other repair factors, thereby facilitating the non-homologous end joining (NHEJ) pathway. Ku70′s importance in cellular processes is underscored by involvement in transcriptional regulation, where Ku70 aids in the phosphorylation of RNA polymerase II and enhances the transcription of specific genes, including those related to cell growth and survival. Additionally, Ku70 has been implicated in various diseases, including cancer and autoimmune disorders, making Ku70 a significant target for research and therapeutic interventions. anti-Ku70 antibody (G-4) is an essential tool for studying these critical biological processes and understanding the implications of Ku70 in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ku70 Antibody (G-4) | sc-166386 | 200 µg/ml | $322.00 | |||
Ku70 Antibody (G-4): m-IgG Fc BP-HRP Bundle | sc-537482 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ku70 Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-534761 | 200 µg Ab; 40 µg BP | $361.00 | |||
Ku70 Antibody (G-4): m-IgG2b BP-HRP Bundle | sc-549880 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ku70 (G-4) Neutralizing Peptide | sc-166386 P | 100 µg/0.5 ml | $69.00 |