Ku70 Antibody (N3H10): sc-56129
- Ku70 Antibody (N3H10) is a mouse monoclonal IgG2b κ, cited in 22 publications, provided at 200 µg/ml
- raised against PSE1-PL human placental cells
- Ku70 Antibody (N3H10) is recommended for detection of Ku70 of mouse, rat, human and Xenopus origin by WB, IP, IF and IHC(P)
- Anti-Ku70 Antibody (N3H10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for Ku70 Antibody (N3H10) for WB and IHC(P) applications. These reagents are now offered in bundles with Ku70 Antibody (N3H10) (see ordering information below).
Ku70 Antibody (N3H10) is a mouse monoclonal IgG2b kappa light chain antibody that detects Ku70 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Ku70 antibody (N3H10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Ku70, a critical component of the Ku heterodimer alongside Ku86, plays a vital role in the cellular response to DNA damage, particularly in the non-homologous end joining (NHEJ) repair pathway. This pathway maintains genomic stability by repairing double-strand breaks in DNA, which can arise from various sources, including ionizing radiation and oxidative stress. Ku70 binding to DNA ends facilitates recruitment of repair factors and protects DNA from degradation. Ku70 also regulates transcription and cell signaling, highlighting a multifaceted role in cellular processes. Ku70 (N3H10) antibody enables researchers to study DNA repair mechanisms and their implications in diseases such as cancer, where DNA repair pathways are often dysregulated.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ku70 Antibody (N3H10) | sc-56129 | 200 µg/ml | $322.00 | |||
Ku70 Antibody (N3H10): m-IgG Fc BP-HRP Bundle | sc-525649 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ku70 Antibody (N3H10): m-IgG2b BP-HRP Bundle | sc-549605 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ku70 Antibody (N3H10) AC | sc-56129 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Ku70 Antibody (N3H10) HRP | sc-56129 HRP | 200 µg/ml | $322.00 | |||
Ku70 Antibody (N3H10) FITC | sc-56129 FITC | 200 µg/ml | $336.00 | |||
Ku70 Antibody (N3H10) PE | sc-56129 PE | 200 µg/ml | $349.00 | |||
Ku70 Antibody (N3H10) Alexa Fluor® 488 | sc-56129 AF488 | 200 µg/ml | $364.00 | |||
Ku70 Antibody (N3H10) Alexa Fluor® 546 | sc-56129 AF546 | 200 µg/ml | $364.00 | |||
Ku70 Antibody (N3H10) Alexa Fluor® 594 | sc-56129 AF594 | 200 µg/ml | $364.00 | |||
Ku70 Antibody (N3H10) Alexa Fluor® 647 | sc-56129 AF647 | 200 µg/ml | $364.00 | |||
Ku70 Antibody (N3H10) Alexa Fluor® 680 | sc-56129 AF680 | 200 µg/ml | $364.00 | |||
Ku70 Antibody (N3H10) Alexa Fluor® 790 | sc-56129 AF790 | 200 µg/ml | $364.00 |