Date published: 2026-1-30

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IRF CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. IRF gene silencers are available as IRF CRISPR/Cas9 Knockout plasmids and IRF Double Nickase Plasmids. IRF CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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IRF CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRF-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400551-KO-2hGene KnockoutGFP0
(0)

IRF-1 HDR Plasmid (h2)

sc-400551-HDR-2hHomology Directed RepairPuromycin0
(0)

IRF-1 Double Nickase Plasmid (h)

sc-400551-NIChGene KnockoutPuromycin0
(0)

IRF-1 Double Nickase Plasmid (h2)

sc-400551-NIC-2hGene KnockoutPuromycin0
(0)

IRF-1 CRISPR/Cas9 KO Plasmid (m)

sc-421146mGene KnockoutGFP0
(0)

IRF-1 HDR Plasmid (m)

sc-421146-HDRmHomology Directed RepairPuromycin0
(0)

IRF-1 Double Nickase Plasmid (m)

sc-421146-NICmGene KnockoutPuromycin0
(0)

IRF-1 CRISPR/Cas9 KO Plasmid (r)

sc-437365rGene KnockoutGFP0
(0)

IRF-2 Double Nickase Plasmid (h)

sc-402135-NIChGene KnockoutPuromycin0
(0)

IRF-2 Double Nickase Plasmid (h2)

sc-402135-NIC-2hGene KnockoutPuromycin0
(0)

IRF-2 CRISPR/Cas9 KO Plasmid (m2)

sc-421147-KO-2mGene KnockoutGFP0
(0)

IRF-2 HDR Plasmid (m2)

sc-421147-HDR-2mHomology Directed RepairPuromycin0
(0)

IRF3 CRISPR/Cas9 KO Plasmid (h)

sc-417171hGene KnockoutGFP
1
(0)

IRF3 HDR Plasmid (h)

sc-417171-HDRhHomology Directed RepairPuromycin
1
(0)

IRF3 Double Nickase Plasmid (h)

sc-417171-NIChGene KnockoutPuromycin
1
(0)

IRF3 Double Nickase Plasmid (h2)

sc-417171-NIC-2hGene KnockoutPuromycin
1
(0)

IRF3 Double Nickase Plasmid (m)

sc-424792-NICmGene KnockoutPuromycin0
(0)

IRF-4 CRISPR/Cas9 KO Plasmid (h)

sc-400288hGene KnockoutGFP0
(0)

IRF-4 HDR Plasmid (h)

sc-400288-HDRhHomology Directed RepairPuromycin0
(0)

IRF-4 Double Nickase Plasmid (h)

sc-400288-NIChGene KnockoutPuromycin0
(0)

IRF-4 Double Nickase Plasmid (h2)

sc-400288-NIC-2hGene KnockoutPuromycin0
(0)

IRF-4 CRISPR/Cas9 KO Plasmid (m)

sc-421148mGene KnockoutGFP0
(0)

IRF-4 HDR Plasmid (m)

sc-421148-HDRmHomology Directed RepairPuromycin0
(0)

IRF-5 CRISPR/Cas9 KO Plasmid (h)

sc-400920hGene KnockoutGFP0
(0)

IRF-5 HDR Plasmid (h)

sc-400920-HDRhHomology Directed RepairPuromycin0
(0)

IRF-5 Double Nickase Plasmid (h)

sc-400920-NIChGene KnockoutPuromycin0
(0)

IRF-5 Double Nickase Plasmid (h2)

sc-400920-NIC-2hGene KnockoutPuromycin0
(0)

IRF-5 CRISPR/Cas9 KO Plasmid (m)

sc-424184mGene KnockoutGFP0
(0)

IRF-7 CRISPR/Cas9 KO Plasmid (h2)

sc-400450-KO-2hGene KnockoutGFP0
(0)

IRF-7 HDR Plasmid (h2)

sc-400450-HDR-2hHomology Directed RepairPuromycin0
(0)

IRF-7 Double Nickase Plasmid (h)

sc-400450-NIChGene KnockoutPuromycin0
(0)

IRF-7 Double Nickase Plasmid (h2)

sc-400450-NIC-2hGene KnockoutPuromycin0
(0)

IRF-7 CRISPR/Cas9 KO Plasmid (m)

sc-424785mGene KnockoutGFP0
(0)

IRF-7 HDR Plasmid (m)

sc-424785-HDRmHomology Directed RepairPuromycin0
(0)

IRF-7 Double Nickase Plasmid (m)

sc-424785-NICmGene KnockoutPuromycin0
(0)

IRF-7 Double Nickase Plasmid (m2)

sc-424785-NIC-2mGene KnockoutPuromycin0
(0)

IRF-2BP2 Double Nickase Plasmid (h)

sc-406153-NIChGene KnockoutPuromycin0
(0)

IRF-2BP2 Double Nickase Plasmid (h2)

sc-406153-NIC-2hGene KnockoutPuromycin0
(0)

IRF-2BP2 Double Nickase Plasmid (m)

sc-435407-NICmGene KnockoutPuromycin0
(0)

IRF CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRF-1 CRISPR Activation Plasmid (h)

sc-400551-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRF-1 CRISPR Activation Plasmid (h2)

sc-400551-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRF-1 Lentiviral Activation Particles (h)

sc-400551-LAChGene ActivationPuro, Blast, Hygro0
(0)

IRF-1 Lentiviral Activation Particles (h2)

sc-400551-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IRF-1 CRISPR Activation Plasmid (r)

sc-437365-ACTrGene ActivationPuro, Blast, Hygro0
(0)

IRF-1 CRISPR Activation Plasmid (r2)

sc-437365-ACT-2rGene ActivationPuro, Blast, Hygro0
(0)

IRF-2 CRISPR Activation Plasmid (h)

sc-402135-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRF-2 CRISPR Activation Plasmid (h2)

sc-402135-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRF3 CRISPR Activation Plasmid (h)

sc-417171-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IRF-4 CRISPR Activation Plasmid (h)

sc-400288-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRF-4 CRISPR Activation Plasmid (h2)

sc-400288-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRF-4 CRISPR Activation Plasmid (m)

sc-421148-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRF-4 Lentiviral Activation Particles (m)

sc-421148-LACmGene ActivationPuro, Blast, Hygro0
(0)

IRF-5 CRISPR Activation Plasmid (h)

sc-400920-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRF-5 CRISPR Activation Plasmid (h2)

sc-400920-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRF-7 CRISPR Activation Plasmid (h)

sc-400450-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRF-7 CRISPR Activation Plasmid (h2)

sc-400450-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRF-7 Lentiviral Activation Particles (h)

sc-400450-LAChGene ActivationPuro, Blast, Hygro0
(0)

IRF-7 CRISPR Activation Plasmid (m)

sc-424785-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRF-7 CRISPR Activation Plasmid (m2)

sc-424785-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)