Date published: 2025-11-21

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insulin R Inhibitors

Insulin R inhibitors belong to a notable chemical class within the realm of bioactive compounds. These inhibitors are characterized by their ability to modulate the functioning of the insulin receptor (IR), a critical protein found on the surface of various cell types in the body. The insulin receptor plays a central role in the regulation of glucose metabolism, as it mediates the uptake of glucose from the bloodstream into cells and is involved in several intracellular signaling pathways. Insulin R inhibitors specifically target this receptor, affecting its activation and downstream signaling cascades. Chemically, insulin R inhibitors often possess intricate molecular structures, enabling them to interact selectively with the insulin receptor's binding sites. These compounds may act through competitive or allosteric mechanisms to interfere with the receptor's normal interaction with insulin molecules. The structural diversity within the class of insulin R inhibitors allows for a range of binding affinities and mechanisms of action, contributing to the nuanced modulation of insulin signaling. Researchers have extensively explored the structure-activity relationships of insulin R inhibitors to elucidate the molecular determinants that govern their interaction with the receptor. This understanding has paved the way for the design and synthesis of novel compounds with enhanced specificity and potency. Additionally, studies on the mechanisms underlying insulin resistance have highlighted the significance of insulin R inhibitors in deciphering the complexities of cellular signaling networks.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AG 1024

65678-07-1sc-205907
1 mg
$105.00
22
(1)

This compound is known to inhibit the insulin receptor and has been used in research to understand insulin-related pathways.

Hypericin

548-04-9sc-3530
sc-3530A
1 mg
5 mg
$65.00
$210.00
11
(1)

Hypericin (CAS 548-04-9) is a chemical compound that acts as an inhibitor of insulin receptor (R). It affects the insulin signaling pathway without invoking any potential medical applications.

BMS-536924

468740-43-4sc-507397
5 mg
$285.00
(0)

This is a small molecule insulin receptor inhibitor that has shown potential in inhibiting insulin signaling pathways.

HNMPA-(AM)3

120944-03-8sc-221730
5 mg
$186.00
12
(1)

HNMPA-(AM)3 (CAS 120944-03-8) is a chemical compound known for its role as an inhibitor of insulin receptor (IR). It interacts with the insulin receptor, modulating its activity through specific mechanisms. This compound's impact on insulin receptor function has been extensively studied in various contexts.

HNMPA

120943-99-9sc-205714
sc-205714A
5 mg
25 mg
$97.00
$386.00
11
(1)

HNMPA (CAS 120943-99-9) is a chemical compound known for its role as an inhibitor of insulin R. It interacts with insulin receptors, modulating their activity. This compound's mechanism of action involves interference with insulin receptor function, affecting cellular signaling pathways. It is extensively studied for its effects on insulin-related processes.

AGL 2263

sc-221223
5 mg
$350.00
1
(1)

AGL 2263 is a chemical compound known for its role as an inhibitor of insulin receptor (R). It modulates insulin signaling pathways, impacting cellular responses. The compound's actions are of interest due to their effects on insulin-related processes.

5-Iodotubercidin

24386-93-4sc-3531
sc-3531A
1 mg
5 mg
$150.00
$455.00
20
(2)

5-Iodotubercidin (CAS 24386-93-4) is a chemical compound known for its role as an inhibitor of insulin receptor (R). It affects the insulin signaling pathway, exerting an impact on cellular processes. The compound's interaction with the insulin receptor has implications for various biological functions.

GSK1838705A

1116235-97-2sc-364502
sc-364502A
5 mg
50 mg
$240.00
$992.00
(0)

An investigational drug that acts as an insulin receptor kinase inhibitor, potentially offering therapeutic benefits for diabetes and related conditions.

Linsitinib

867160-71-2sc-396762
sc-396762A
5 mg
10 mg
$143.00
$260.00
1
(0)

An inhibitor of the insulin-like growth factor-1 receptor (IGF-1R) that has been studied for its potential in cancer therapy.

BMS-754807

1001350-96-4sc-507396
5 mg
$304.00
(0)

Another IGF-1R inhibitor that has shown promise in laboratory studies for its anti-tumor effects.