Date published: 2025-11-21

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insulin R Substrates

Santa Cruz Biotechnology now offers a broad range of insulin R substrates for use in various applications. Insulin R substrates are a class of biochemical compounds that interact specifically with the insulin receptor (IR), a critical player in the regulation of glucose homeostasis. In scientific research, these substrates are invaluable for studying the molecular mechanisms underlying insulin signaling pathways. Researchers utilize insulin R substrates to explore the phosphorylation events and downstream signaling cascades triggered by insulin binding to its receptor. This exploration is crucial for understanding the regulation of metabolic processes at the cellular level, as well as for investigating the role of insulin signaling in various physiological conditions. The precise measurement and manipulation of these substrates enable detailed studies of enzyme kinetics, receptor-ligand interactions, and signal transduction pathways. Furthermore, insulin R substrates are employed in the development of bioassays and diagnostic tools to measure insulin sensitivity and receptor functionality in cell lines and tissues. The availability of these substrates enhances the ability of researchers to dissect the complexities of insulin action and its broader implications in metabolic regulation and cellular signaling networks. View detailed information on our available insulin R substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Insulin Receptor Substrate

sc-3048
0.5 mg
$95.00
(0)

Insulin Receptor Substrate (IRS) is a pivotal signaling molecule that mediates insulin's effects on cellular metabolism. It features multiple phosphorylation sites that facilitate interactions with various signaling proteins, enhancing the activation of pathways like PI3K and MAPK. The IRS's structural flexibility allows it to adapt to different receptor conformations, optimizing its role in transducing insulin signals. Its dynamic interactions are crucial for regulating glucose uptake and metabolic homeostasis.

bpV(phen)

171202-16-7sc-221378
sc-221378A
5 mg
25 mg
$96.00
$286.00
10
(1)

bpV(phen) is a selective inhibitor of protein tyrosine phosphatases, particularly impacting the insulin receptor signaling pathway. It exhibits unique binding affinity, stabilizing phosphorylated states of proteins, which enhances insulin receptor activity. This compound modulates downstream signaling cascades by altering the kinetics of phosphorylation and dephosphorylation processes, thereby influencing cellular responses to insulin. Its distinct molecular interactions contribute to the fine-tuning of metabolic regulation.