Date published: 2026-7-10

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Histone CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Histone gene silencers are available as Histone CRISPR/Cas9 Knockout plasmids and Histone Double Nickase Plasmids. Histone CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Histone CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Histone H2A.X CRISPR/Cas9 KO Plasmid (h)

sc-400538Gene Knockouth0
(0)

Histone cluster 1 H1E CRISPR/Cas9 KO Plasmid (h)

sc-402775Gene Knockouth0
(0)

Histone H10 CRISPR/Cas9 KO Plasmid (h)

sc-403716Gene Knockouth0
(0)

Histone H1 CRISPR/Cas9 KO Plasmid (h)

sc-404845Gene Knockouth0
(0)

Histone H2A.Z CRISPR/Cas9 KO Plasmid (h)

sc-406087Gene Knockouth0
(0)

Histone cluster 1 H1C CRISPR/Cas9 KO Plasmid (h)

sc-407712Gene Knockouth0
(0)

Histone H3.3B CRISPR/Cas9 KO Plasmid (h)

sc-410815Gene Knockouth0
(0)

Histone H1X CRISPR/Cas9 KO Plasmid (h)

sc-411232Gene Knockouth0
(0)

Histone H3.3A CRISPR/Cas9 KO Plasmid (h)

sc-416802Gene Knockouth0
(0)

Histone H10 CRISPR/Cas9 KO Plasmid (m)

sc-420754Gene Knockoutm0
(0)

Histone H2A.X HDR Plasmid (h)

sc-400538-HDRHomology Directed Repairh0
(0)

Histone H10 HDR Plasmid (h)

sc-403716-HDRHomology Directed Repairh0
(0)

Histone H1 HDR Plasmid (h)

sc-404845-HDRHomology Directed Repairh0
(0)

Histone H2A.Z HDR Plasmid (h)

sc-406087-HDRHomology Directed Repairh0
(0)

Histone cluster 1 H1C HDR Plasmid (h)

sc-407712-HDRHomology Directed Repairh0
(0)

Histone H3.3B HDR Plasmid (h)

sc-410815-HDRHomology Directed Repairh0
(0)

Histone H3.3A HDR Plasmid (h)

sc-416802-HDRHomology Directed Repairh0
(0)

Histone H2A.Z CRISPR/Cas9 KO Plasmid (m2)

sc-424549-KO-2Gene Knockoutm0
(0)

Histone H2A.Z HDR Plasmid (m2)

sc-424549-HDR-2Homology Directed Repairm0
(0)

Histone CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Histone H2A.X Double Nickase Plasmid (h)

sc-400538-NICGene Knockouth0
(0)

Histone cluster 1 H1E Double Nickase Plasmid (h)

sc-402775-NICGene Knockouth0
(0)

Histone H10 Double Nickase Plasmid (h)

sc-403716-NICGene Knockouth0
(0)

Histone H1 Double Nickase Plasmid (h)

sc-404845-NICGene Knockouth0
(0)

Histone cluster 1 H1D Double Nickase Plasmid (h)

sc-408739-NICGene Knockouth0
(0)

Histone H1X Double Nickase Plasmid (h)

sc-411232-NICGene Knockouth0
(0)

Histone H3.3A Double Nickase Plasmid (h)

sc-416802-NICGene Knockouth0
(0)

Histone cluster 1 H2BK Double Nickase Plasmid (h)

sc-417678-NICGene Knockouth0
(0)

Histone H3.3A Double Nickase Plasmid (m)

sc-420787-NICGene Knockoutm0
(0)

Histone H2A.Z Double Nickase Plasmid (m)

sc-424549-NICGene Knockoutm0
(0)

Histone H2A.X Double Nickase Plasmid (h2)

sc-400538-NIC-2Gene Knockouth0
(0)

Histone cluster 1 H1E Double Nickase Plasmid (h2)

sc-402775-NIC-2Gene Knockouth0
(0)

Histone H10 Double Nickase Plasmid (h2)

sc-403716-NIC-2Gene Knockouth0
(0)

Histone H1 Double Nickase Plasmid (h2)

sc-404845-NIC-2Gene Knockouth0
(0)

Histone H1X Double Nickase Plasmid (h2)

sc-411232-NIC-2Gene Knockouth0
(0)

Histone H3.3A Double Nickase Plasmid (h2)

sc-416802-NIC-2Gene Knockouth0
(0)

Histone cluster 1 H2BK Double Nickase Plasmid (h2)

sc-417678-NIC-2Gene Knockouth0
(0)

Histone H3.3A Double Nickase Plasmid (m2)

sc-420787-NIC-2Gene Knockoutm0
(0)

Histone H2A.Z Double Nickase Plasmid (m2)

sc-424549-NIC-2Gene Knockoutm0
(0)

Histone CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Histone H2A.X CRISPR Activation Plasmid (h)

sc-400538-ACTGene Activationh0
(0)

Histone cluster 1 H1E CRISPR Activation Plasmid (h)

sc-402775-ACTGene Activationh0
(0)

Histone H10 CRISPR Activation Plasmid (h)

sc-403716-ACTGene Activationh0
(0)

Histone H1 CRISPR Activation Plasmid (h)

sc-404845-ACTGene Activationh0
(0)

Histone H1X CRISPR Activation Plasmid (h)

sc-411232-ACTGene Activationh0
(0)

Histone cluster 1 H3A CRISPR Activation Plasmid (m)

sc-436164-ACTGene Activationm0
(0)

Histone cluster 1 H1E CRISPR Activation Plasmid (h2)

sc-402775-ACT-2Gene Activationh0
(0)

Histone H10 CRISPR Activation Plasmid (h2)

sc-403716-ACT-2Gene Activationh0
(0)

Histone H1X CRISPR Activation Plasmid (h2)

sc-411232-ACT-2Gene Activationh0
(0)