Date published: 2026-5-10

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GCS-α-1 Activators

The chemical class called GCS-α-1 Activators would include compounds that indirectly influence the activity of GCS-α-1 by modulating lipid metabolism and cellular signaling pathways. These chemicals do not directly interact with GCS-α-1 but could create conditions favorable for its activity or modulate related pathways. Compounds like Metformin, Forskolin, Simvastatin, and Pioglitazone could affect lipid metabolism and biosynthesis, pathways that are crucial for ganglioside synthesis. Metformin, through its action on AMPK, and Pioglitazone, as a PPAR-gamma agonist, can influence lipid metabolic processes. Forskolin, by increasing cAMP levels, and Simvastatin, by inhibiting cholesterol biosynthesis, could indirectly modulate ganglioside synthesis.

Additionally, compounds like Curcumin, Niacin, Palmitic Acid, and Omega-3 Fatty Acids could impact lipid metabolism and cellular membrane dynamics, influencing ganglioside synthesis. Resveratrol and Caffeine, known for their broad spectrum of biological effects, could indirectly impact signaling pathways relevant to lipid metabolism. Furthermore, Glucosamine and Retinoic Acid, through their roles in glycosaminoglycan synthesis and gene expression regulation, respectively, might also influence the biosynthetic pathways involved in ganglioside synthesis.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

An AMPK activator, could potentially influence lipid metabolism pathways, indirectly affecting ganglioside synthesis.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Increases cAMP levels, possibly affecting signaling pathways that could indirectly influence ganglioside synthesis.

Simvastatin

79902-63-9sc-200829
sc-200829A
sc-200829B
sc-200829C
50 mg
250 mg
1 g
5 g
$31.00
$89.00
$135.00
$443.00
13
(1)

An HMG-CoA reductase inhibitor, may influence cholesterol biosynthesis, potentially impacting pathways related to ganglioside synthesis.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

A PPAR-gamma agonist, could influence lipid metabolism and indirectly affect ganglioside synthesis.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

May influence lipid metabolism and cellular signaling pathways, potentially affecting ganglioside synthesis.

Nicotinic Acid

59-67-6sc-205768
sc-205768A
250 g
500 g
$62.00
$124.00
1
(1)

Affects lipid metabolism, potentially influencing the biosynthesis of gangliosides.

Palmitic Acid

57-10-3sc-203175
sc-203175A
25 g
100 g
$114.00
$286.00
2
(0)

A fatty acid that could potentially influence lipid biosynthetic pathways, including those involved in ganglioside synthesis.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Influences various signaling pathways; could indirectly impact pathways involved in ganglioside synthesis.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Affects various cellular signaling pathways, potentially influencing metabolic processes related to ganglioside synthesis.

D-Glucosamine

3416-24-8sc-278917A
sc-278917
1 g
10 g
$201.00
$779.00
(0)

Involved in glycosaminoglycan synthesis, could indirectly influence ganglioside synthesis.