GABA T-2 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(S)-SNAP 5114 | 157604-55-2 | sc-204257 sc-204257A | 5 mg 25 mg | $173.00 $571.00 | ||
(S)-SNAP 5114 acts as a GABA transaminase inhibitor, exhibiting a distinctive mechanism that alters neurotransmitter metabolism. This compound selectively binds to the enzyme, leading to a reduction in GABA degradation and an increase in its availability. The reaction kinetics reveal a competitive inhibition pattern, enhancing GABAergic signaling. Additionally, (S)-SNAP 5114's structural features allow for specific interactions with active site residues, influencing enzyme conformation and activity. | ||||||
Vigabatrin | 60643-86-9 | sc-204382 sc-204382A sc-204382B sc-204382C | 10 mg 50 mg 100 mg 1 g | $125.00 $485.00 $650.00 $1015.00 | 2 | |
Irreversible GABA transaminase inhibitor, directly inhibits GABA T-2, leading to an increase in GABA levels. | ||||||
NNC 05-2090 hydrochloride | 184845-43-0 | sc-204131 sc-204131A | 10 mg 50 mg | $235.00 $978.00 | ||
NNC 05-2090 hydrochloride functions as a GABA transaminase inhibitor, characterized by its unique binding affinity to the enzyme's active site. This compound exhibits a non-competitive inhibition profile, modulating the enzymatic activity without competing directly with the substrate. Its structural attributes facilitate distinct molecular interactions, stabilizing the enzyme in a conformation that reduces GABA catabolism, thereby influencing metabolic pathways and neurotransmitter dynamics. | ||||||
Phenethyl-hydrazine | 51-71-8 | sc-331686 | 500 mg | $396.00 | ||
MAO inhibitor also known to inhibit GABA transaminase. Inhibits degradation of GABA, affecting GABA T-2 function indirectly. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Inhibits GABA transaminase, elevating GABA levels and inhibiting GABA T-2. | ||||||
Lamotrigine | 84057-84-1 | sc-201079 sc-201079A | 10 mg 50 mg | $120.00 $486.00 | 1 | |
Modulates voltage-gated sodium channels, indirectly influences GABA T-2 by stabilizing neuronal membranes and enhancing GABA availability. | ||||||
Riluzole | 1744-22-5 | sc-201081 sc-201081A sc-201081B sc-201081C | 20 mg 100 mg 1 g 25 g | $20.00 $193.00 $213.00 $317.00 | 1 | |
Inhibits voltage-gated sodium channels and glutamate release; influences GABA T-2 by stabilizing cellular excitability. | ||||||
(±)-Baclofen | 1134-47-0 | sc-200464 sc-200464A | 1 g 5 g | $56.00 $258.00 | ||
GABA(B) receptor agonist; inhibits cAMP formation, leading to decreased intracellular calcium and modulating GABA T-2 action. | ||||||
Muscimol | 2763-96-4 | sc-200460 sc-200460A | 5 mg 25 mg | $161.00 $537.00 | 2 | |
GABA(A) receptor agonist; influences GABA T-2 by reducing GABA reuptake, leading to higher extracellular GABA levels. | ||||||
L-NG-Nitroarginine Methyl Ester (L-NAME) | 51298-62-5 | sc-200333 sc-200333A sc-200333B | 1 g 5 g 25 g | $48.00 $107.00 $328.00 | 45 | |
NOS inhibitor that decreases nitric oxide, which regulates GABAergic signaling, thereby affecting GABA T-2 indirectly. | ||||||