Date published: 2026-3-2

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dsg Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of dsg Antibodies for understanding desmogleins (dsg), crucial components of desmosomes that mediate cell-cell adhesion in epithelial tissues. Monoclonal dsg Antibodies are suitable for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Desmogleins play a vital role in maintaining the structural integrity of tissues and are implicated in various diseases, including pemphigus vulgaris, an autoimmune disorder characterized by blistering of the skin and mucous membranes. Understanding the function and regulation of desmogleins is essential for developing targeted therapies and advancing knowledge of cell adhesion mechanisms. Dsg Antibodies enable researchers to investigate cellular pathways and molecular interactions involved in tissue development and disease progression. Monoclonal dsg Antibodies support detailed analysis of protein expression patterns and localization in different tissue types. Advanced research with dsg Antibodies from Santa Cruz Biotechnology continues to drive discoveries in cell adhesion biology and contribute to the development of new therapeutic strategies.

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dsg Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

dsg1 Antibody (B-11)

sc-137164mouse IgG2b κ760-1049 (h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(10)

dsg1 Antibody (27B2)

sc-59904mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
4
(2)

dsg2 Antibody (AH12.2)

sc-80663mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
17
(6)

dsg2 Antibody (F-8)

sc-365856mouse IgG1 κ816-960 (h)WB, IP, IF, ELISAm, r, h
1
(2)

dsg2 Antibody (6D8)

sc-53486mouse IgG1 κFL (h)WB, IP, IFh
7
(2)

dsg2 Antibody (F-5)

sc-390531mouse IgG1 κ1011-1035 (h)WB, IP, IF, ELISAm, r, h

new

(4)

dsg2 Antibody (13B11)

sc-135815mouse IgG1 κ37-164 (h)WB, IPh

new

(1)

dsg3 Antibody (5H10)

sc-23912mouse IgG1 κ(h)WB, IP, IFh
19
(3)

dsg3 Antibody (5G11)

sc-53487mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
6
(4)

dsg3 Antibody (3G133)

sc-59776mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
3
(2)

dsg4 Antibody (6E7)

sc-517109mouse IgG1 κ531-630 (h)WB, IP, ELISAh

new

(1)

dsg CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

dsg1 CRISPR/Cas9 KO Plasmid (h)

sc-401442hGene KnockoutGFP0
(0)

dsg1 Double Nickase Plasmid (h)

sc-401442-NIChGene KnockoutPuromycin0
(0)

dsg1 Double Nickase Plasmid (h2)

sc-401442-NIC-2hGene KnockoutPuromycin0
(0)

dsg2 CRISPR/Cas9 KO Plasmid (h)

sc-400957hGene KnockoutGFP0
(0)

dsg2 HDR Plasmid (h)

sc-400957-HDRhHomology Directed RepairPuromycin0
(0)

dsg2 Double Nickase Plasmid (h)

sc-400957-NIChGene KnockoutPuromycin0
(0)

dsg2 Double Nickase Plasmid (h2)

sc-400957-NIC-2hGene KnockoutPuromycin0
(0)

dsg2 CRISPR/Cas9 KO Plasmid (m)

sc-420067mGene KnockoutGFP0
(0)

dsg2 HDR Plasmid (m)

sc-420067-HDRmHomology Directed RepairPuromycin0
(0)

dsg3 CRISPR/Cas9 KO Plasmid (h)

sc-401809hGene KnockoutGFP0
(0)

dsg3 CRISPR/Cas9 KO Plasmid (h2)

sc-401809-KO-2hGene KnockoutGFP0
(0)

dsg3 HDR Plasmid (h2)

sc-401809-HDR-2hHomology Directed RepairPuromycin0
(0)

dsg3 Double Nickase Plasmid (h)

sc-401809-NIChGene KnockoutPuromycin0
(0)

dsg3 Double Nickase Plasmid (h2)

sc-401809-NIC-2hGene KnockoutPuromycin0
(0)

dsg4 CRISPR/Cas9 KO Plasmid (h)

sc-405824hGene KnockoutGFP0
(0)

dsg4 HDR Plasmid (h)

sc-405824-HDRhHomology Directed RepairPuromycin0
(0)

dsg CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

dsg1 CRISPR Activation Plasmid (h)

sc-401442-ACThGene ActivationPuro, Blast, Hygro0
(0)

dsg1 CRISPR Activation Plasmid (h2)

sc-401442-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

dsg2 CRISPR Activation Plasmid (h)

sc-400957-ACThGene ActivationPuro, Blast, Hygro0
(0)

dsg2 Lentiviral Activation Particles (h)

sc-400957-LAChGene ActivationPuro, Blast, Hygro0
(0)

dsg3 CRISPR Activation Plasmid (h)

sc-401809-ACThGene ActivationPuro, Blast, Hygro0
(0)

dsg siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

dsg1 siRNA (h)

sc-35224hGene SilencingN/A
2
(0)

dsg1 shRNA Plasmid (h)

sc-35224-SHhGene SilencingPuromycin
2
(0)

dsg1 shRNA (h) Lentiviral Particles

sc-35224-VhGene SilencingPuromycin
2
(0)

dsg2 siRNA (h)

sc-35226hGene SilencingN/A0
(0)

dsg2 shRNA Plasmid (h)

sc-35226-SHhGene SilencingPuromycin0
(0)

dsg2 shRNA (h) Lentiviral Particles

sc-35226-VhGene SilencingPuromycin0
(0)

dsg2 siRNA (m)

sc-35227mGene SilencingN/A0
(0)

dsg2 shRNA Plasmid (m)

sc-35227-SHmGene SilencingPuromycin0
(0)

dsg2 shRNA (m) Lentiviral Particles

sc-35227-VmGene SilencingPuromycin0
(0)

dsg2 siRNA (r)

sc-270373rGene SilencingN/A0
(0)

dsg2 shRNA Plasmid (r)

sc-270373-SHrGene SilencingPuromycin0
(0)

dsg2 shRNA (r) Lentiviral Particles

sc-270373-VrGene SilencingPuromycin0
(0)

dsg3 siRNA (h)

sc-43115hGene SilencingN/A
1
(0)

dsg3 shRNA Plasmid (h)

sc-43115-SHhGene SilencingPuromycin
1
(0)

dsg3 shRNA (h) Lentiviral Particles

sc-43115-VhGene SilencingPuromycin
1
(0)

dsg3 siRNA (m)

sc-43116mGene SilencingN/A0
(0)

dsg3 shRNA Plasmid (m)

sc-43116-SHmGene SilencingPuromycin0
(0)

dsg3 shRNA (m) Lentiviral Particles

sc-43116-VmGene SilencingPuromycin0
(0)

dsg4 siRNA (h)

sc-44763hGene SilencingN/A0
(0)

dsg4 shRNA Plasmid (h)

sc-44763-SHhGene SilencingPuromycin0
(0)

dsg4 shRNA (h) Lentiviral Particles

sc-44763-VhGene SilencingPuromycin0
(0)

dsg4 siRNA (m)

sc-44764mGene SilencingN/A0
(0)

dsg4 shRNA Plasmid (m)

sc-44764-SHmGene SilencingPuromycin0
(0)

dsg4 shRNA (m) Lentiviral Particles

sc-44764-VmGene SilencingPuromycin0
(0)