Date published: 2026-1-12

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dsg2 Antibodies

Santa Cruz Biotechnology delivers a wide array of dsg2 monoclonal antibodies for researching desmoglein 2 (dsg2) and its role in cellular adhesion. dsg2 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Desmoglein 2 is a crucial component of desmosomes, which are structures that provide strong adhesion between cells in tissues, particularly in the heart and skin. Desmoglein 2 maintains tissue integrity and participates in various cellular processes, including signaling pathways that regulate cell proliferation and differentiation. Research has shown that dsg2 alterations are linked to several diseases, including autoimmune disorders and certain types of cancer. Understanding dsg2 function and regulation continues to be an active area of investigation in cell biology and disease research. Exploring dsg2's role in tissue development and homeostasis remains crucial for advancing our knowledge of cellular adhesion mechanisms. Current research focuses on understanding how dsg2 modifications influence disease progression and potential therapeutic interventions. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of desmoglein 2's role in health and disease.

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dsg2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

dsg2 Antibody (AH12.2)

sc-80663mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
17
(6)

dsg2 Antibody (F-8)

sc-365856mouse IgG1 κ816-960 (h)WB, IP, IF, ELISAm, r, h
1
(2)

dsg2 Antibody (6D8)

sc-53486mouse IgG1 κFL (h)WB, IP, IFh
7
(2)

dsg2 Antibody (F-5)

sc-390531mouse IgG1 κ1011-1035 (h)WB, IP, IF, ELISAm, r, h

new

(4)

dsg2 Antibody (13B11)

sc-135815mouse IgG1 κ37-164 (h)WB, IPh

new

(1)

dsg2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

dsg2 CRISPR/Cas9 KO Plasmid (h)

sc-400957hGene KnockoutGFP0
(0)

dsg2 HDR Plasmid (h)

sc-400957-HDRhHomology Directed RepairPuromycin0
(0)

dsg2 Double Nickase Plasmid (h)

sc-400957-NIChGene KnockoutPuromycin0
(0)

dsg2 Double Nickase Plasmid (h2)

sc-400957-NIC-2hGene KnockoutPuromycin0
(0)

dsg2 CRISPR/Cas9 KO Plasmid (m)

sc-420067mGene KnockoutGFP0
(0)

dsg2 HDR Plasmid (m)

sc-420067-HDRmHomology Directed RepairPuromycin0
(0)

dsg2 Double Nickase Plasmid (m)

sc-420067-NICmGene KnockoutPuromycin0
(0)

dsg2 Double Nickase Plasmid (m2)

sc-420067-NIC-2mGene KnockoutPuromycin0
(0)

dsg2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

dsg2 CRISPR Activation Plasmid (h)

sc-400957-ACThGene ActivationPuro, Blast, Hygro0
(0)

dsg2 CRISPR Activation Plasmid (h2)

sc-400957-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

dsg2 Lentiviral Activation Particles (h)

sc-400957-LAChGene ActivationPuro, Blast, Hygro0
(0)

dsg2 Lentiviral Activation Particles (h2)

sc-400957-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

dsg2 CRISPR Activation Plasmid (m)

sc-420067-ACTmGene ActivationPuro, Blast, Hygro0
(0)

dsg2 CRISPR Activation Plasmid (m2)

sc-420067-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

dsg2 Lentiviral Activation Particles (m)

sc-420067-LACmGene ActivationPuro, Blast, Hygro0
(0)

dsg2 Lentiviral Activation Particles (m2)

sc-420067-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

dsg2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

dsg2 siRNA (h)

sc-35226hGene SilencingN/A0
(0)

dsg2 shRNA Plasmid (h)

sc-35226-SHhGene SilencingPuromycin0
(0)

dsg2 shRNA (h) Lentiviral Particles

sc-35226-VhGene SilencingPuromycin0
(0)

dsg2 siRNA (m)

sc-35227mGene SilencingN/A0
(0)

dsg2 shRNA Plasmid (m)

sc-35227-SHmGene SilencingPuromycin0
(0)

dsg2 shRNA (m) Lentiviral Particles

sc-35227-VmGene SilencingPuromycin0
(0)

dsg2 siRNA (r)

sc-270373rGene SilencingN/A0
(0)

dsg2 shRNA Plasmid (r)

sc-270373-SHrGene SilencingPuromycin0
(0)

dsg2 shRNA (r) Lentiviral Particles

sc-270373-VrGene SilencingPuromycin0
(0)