DACH1 Inhibitors
DACH1 inhibitors belong to a chemical class of compounds that have been developed to specifically target and modulate the activity of the DACH1 protein. DACH1, also known as dachshund homolog 1, is a transcriptional factor that plays a critical role in various cellular processes and signaling pathways. These inhibitors are designed to interact with the DACH1 protein, binding to specific sites on the protein's structure. By doing so, they disrupt the normal interactions and functions of DACH1 within the cell. The mechanism of action of DACH1 inhibitors can vary depending on the specific compound, but their overall objective is to inhibit or modulate the activity of the DACH1 protein.
Researchers have been studying DACH1 inhibitors to gain a deeper understanding of their impact on various biological processes and signaling pathways regulated by DACH1. By selectively inhibiting DACH1, these compounds have the potential to influence key cellular processes such as cell differentiation, proliferation, and survival. Additionally, since DACH1 is involved in multiple signaling pathways, targeting this protein with inhibitors may have wide-ranging effects on cellular functions. It is worth noting that the field of DACH1 inhibitors is still actively evolving, and further research is required to fully elucidate the potential applications and consequences of targeting DACH1 using these compounds.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram has shown inhibitory effects on Dach1 expression and its downstream signaling pathways in certain cell lines. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 is a bromodomain and extraterminal domain (BET) inhibitor that has been shown to downregulate Dach1 expression and inhibit its transcriptional activity in cells. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat is a histone deacetylase inhibitor that has been found to suppress Dach1 expression and promote cancer cell growth inhibition in certain studies. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a natural compound found in turmeric, has been shown to inhibit Dach1 expression and enhance the effects in various cell lines. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes and berries, has demonstrated inhibitory effects on Dach1 expression and activation, potentially contributing to its properties. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid abundant in fruits and vegetables, has been reported to downregulate Dach1 expression and inhibit growth in several models. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound found in cruciferous vegetables, has been shown to inhibit Dach1 expression and enhance the effects in certain cell lines. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
Niclosamide, an anthelmintic drug, has demonstrated inhibitory effects on Dach1 expression and has shown potential as an agent in research studies. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid, commonly used as an anticonvulsant, has been found to downregulate Dach1 expression and inhibit growth in certain celltypes. | ||||||
Thioridazine | 50-52-2 | sc-473180 | 50 mg | $500.00 | ||
Thioridazine, an antipsychotic agent in research, has shown inhibitory effects on Dach1 expression and has been investigated for its potential properties. | ||||||