Date published: 2025-10-12

1-800-457-3801

SCBT Portrait Logo
Seach Input

(±)-JQ1 (CAS 1268524-69-1)

0.0(0)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
(±)-SGCBD01; [(R,S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-acetic acid tert-butyl ester
Application:
(±)-JQ1 is a selective BET inhibitor that inhibits Brd4
CAS Number:
1268524-69-1
Purity:
≥98%
Molecular Weight:
456.99
Molecular Formula:
C23H25ClN4O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

(±)-JQ1 is a selective BET inhibitor that inhibits BRD4 (Bromodomain-containing protein 4). Brd4 has been shwn to form complexes with chromatin via two tandem bromodomains that bind to acetylated lysine residues in histones. This may act to regulate the recruitment of elongation factors and other transcription factors to specific promoter regions.


(±)-JQ1 (CAS 1268524-69-1) References

  1. BRD4 inhibition alleviates mechanical stress-induced TMJ OA-like pathological changes and attenuates TREM1-mediated inflammatory response.  |  Huang, Z., et al. 2021. Clin Epigenetics. 13: 10. PMID: 33446277

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-JQ1, 5 mg

sc-472932
5 mg
$226.00

(±)-JQ1, 25 mg

sc-472932A
25 mg
$846.00