Cux2 Activators
Cux2, encoding a protein with three CUT domains and a homeodomain, serves as a DNA-binding motif involved in transcriptional regulation. The CUT domains and homeodomain signify its role as a transcription factor, suggesting a role in modulating gene expression. Cux2's involvement in cellular processes is underscored by its DNA-binding activities, and it plays a crucial part in orchestrating the transcriptional landscape through direct interaction with DNA.
Activation of Cux2 is intricately regulated by both direct and indirect mechanisms. Direct activators include compounds that directly impact the protein or its binding capabilities, potentially leading to enhanced transcriptional activities. On the other hand, indirect activators modulate signaling pathways or cellular processes that influence Cux2 expression and function. For instance, HDAC inhibitors such as Trichostatin A alter histone acetylation patterns, indirectly promoting Cux2 activity by modifying the chromatin structure and affecting the transcriptional regulatory environment. Similarly, DNA demethylating agents like 5-Azacytidine influence DNA methylation patterns, indirectly promoting Cux2 by altering the epigenetic landscape and potentially impacting gene expression patterns. These diverse mechanisms collectively highlight the multifaceted nature of Cux2 activation, emphasizing its pivotal role in transcriptional regulation and cellular processes. Understanding these intricate interactions provides valuable insights into the regulatory networks governing Cux2 and its impact on cellular function and gene expression.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
HDAC inhibitor influencing histone acetylation and chromatin structure, indirectly enhancing Cux2 activity. Modulates gene expression by impacting the epigenetic landscape, potentially activating Cux2 through alterations in the transcriptional regulatory network. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA demethylating agent influencing DNA methylation patterns, indirectly promoting Cux2 activity. Alters the epigenetic status of the genome, potentially leading to changes in Cux2 expression and function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoid receptor agonist influencing gene expression, potentially activating Cux2. Acts on specific retinoid receptors, modulating transcriptional activities and indirectly impacting Cux2 through altered signaling cascades. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
HDAC inhibitor impacting histone acetylation, indirectly enhancing Cux2 activity. Modulates chromatin structure, potentially activating Cux2 through epigenetic modifications that influence the transcriptional regulatory landscape. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
BET bromodomain inhibitor impacting gene expression, potentially influencing Cux2. Targets bromodomain-containing proteins, modulating chromatin structure and indirectly affecting Cux2 activity by altering the transcriptional regulatory environment. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
TGF-β receptor inhibitor indirectly influencing Cux2. Modulates the TGF-β signaling pathway, potentially impacting Cux2 activity through alterations in downstream signaling cascades and gene expression patterns. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
DNA methyltransferase inhibitor indirectly promoting Cux2 activity. Alters DNA methylation patterns, potentially leading to changes in the epigenetic landscape that influence Cux2 expression and function. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
DNA methyltransferase inhibitor influencing DNA methylation patterns, indirectly promoting Cux2 activity. Modifies the epigenetic status of the genome, potentially impacting Cux2 expression and function. | ||||||
PNU-74654 | 113906-27-7 | sc-258020 sc-258020A | 5 mg 25 mg | $128.00 $485.00 | 7 | |
Topoisomerase I inhibitor indirectly impacting Cux2. Modulates DNA topology, potentially influencing Cux2 activity through alterations in DNA structure and chromatin organization. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Microtubule inhibitor indirectly affecting Cux2. Modulates cellular dynamics and potentially influences Cux2 activity by altering signaling cascades related to cytoskeletal organization and cellular function. | ||||||