CT45-3 Activators
CT45-3 activators function through a variety of mechanisms, influencing different pathways and processes to potentially increase the functional activity of CT45-3. Some activators work by modulating the immune response, which could enhance the activity of CT45-3 in immune surveillance. This is achieved, for instance, by increasing intracellular cAMP levels, which in turn activates adenylyl cyclase, a key enzyme in the immune signaling cascade. Other compounds may induce epigenetic changes, such as increased histone acetylation or DNA demethylation, leading to the upregulation of tumor antigens like CT45-3. These epigenetic modifications can occur through the inhibition of histone deacetylases or DNA methyltransferases, altering the chromatin structure and gene expression profile within tumor cells.
Additionally, some activators may modulate gene expression directly through receptor-mediated pathways, such as retinoic acid receptors, leading to the differentiation of immune cells and potentially upregulating CT45-3 expression. Other compounds engage in the upregulation of CT45-3 through the activation of signaling pathways associated with cell proliferation and the immune response, like the Wnt/β-catenin pathway. Moreover, the induction of stress response pathways by increasing reactive oxygen species (ROS) levels or activating Nrf2 signaling can also potentially lead to the increased expression of CT45-3, as the protein might be involved in the cellular adaptive response to oxidative stress.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP levels by activating adenylyl cyclase, which could enhance the immune response including the activity of CT45-3 in immune surveillance. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Histone deacetylase inhibitor that promotes histone acetylation, potentially enhancing the expression of tumor antigens like CT45-3 by affecting chromatin structure. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that leads to demethylation of DNA, possibly resulting in the upregulation of cancer/testis antigens such as CT45-3. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can lead to increased expression of genes involved in immune responses, potentially including the expression of CT45-3. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Sirtuin activator that may affect the expression of tumor antigens, including CT45-3, through epigenetic modifications. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
By modulating gene expression through retinoic acid receptors, it could upregulate CT45-3 expression as part of the differentiation processes of immune cells. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $240.00 | 9 | |
Protein kinase C activator that may induce the expression of cancer/testis antigens like CT45-3 through modulation of immune signaling pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates multiple signaling pathways, which could lead to the upregulation of CT45-3 expression in the context of immune response and cell cycle regulation. | ||||||
Piperlongumine | 20069-09-4 | sc-364128 | 10 mg | $107.00 | ||
Increases ROS levels and may affect the expression of proteins involved in stress responses, including potential upregulation of CT45-3 expression in tumor cells. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
Activates Nrf2 signaling, which may lead to the upregulation of CT45-3 expression due to the role of Nrf2 in the cellular response to oxidative stress. | ||||||