Piperlongumine, isolated from Piper longum, is a cell-permeable inducer of cell-death in cancer cells. It has been shown to inhibit expression of Bcl-2 and enhance wild type p53 expression. Piperlongumine is an inhibitor of GSTP1.
Soluble in DMSO (100 mM), ethanol (20 mM with gentle warming), DMF (~20 mg/ml), 1: 10 DMSO: PBS (pH 7.2) (~0.1 mg/ml), and methanol.
Store at -20° C
~475.6° C at 760 mmHg (Predicted)
~1.2 g/cm3 (Predicted)
n20D 1.58 (Predicted)
Trypanosoma cruzi: IC50 = 21 µM
Platelet aggregation induced by the thromboxane A2 agonist U-46619: Ki= 6.8 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
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mel enviaran desde ALEMANIA?
Asked by: adonis
Thank you for the question. Customers located in Europe will be served by our European Support Office located in Heidelberg Germany. Please contact us to receive a sales quotation with estimated lead time. The product is currently in stock.
Answered by: Technical Support Europe
Date published: 2019-02-11
Dear SCBT Team,
Is product sc-364128 an exact isomer, or a racemate?
Asked by: Peter Zed
Thank you for your question. Please contact our Technical Service Department to request more detailed information about what is in stock currently for this chemical. Please call our European Support office toll-free at 00800 4573 8000, email [email protected], or contact us by live chat.
Rated 5 out of
Wang et alWang et al. (PubMed ID 262466196) found that Piperlongumine induced autophagy and apoptosis in lung cancer cells via PI3K/Akt/mTOR pathway inhibition. -SCBT Publication Review
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