Date published: 2026-4-21

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ARK-2 Activators

ARK-2 activators encompass a variety of chemicals that modulate the activity of ARK-2, providing insights into mechanisms for cellular regulation. Forskolin, a potent adenylyl cyclase activator, stimulates cAMP production, leading to the activation of downstream pathways that modulate ARK-2 activity. A769662, an AMP-activated protein kinase (AMPK) activator, affects cellular energy sensing and can modulate ARK-2 through downstream effects on cellular metabolism and signaling. GW501516, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, activates PPARδ, influencing ARK-2 activity through downstream effects on cellular processes related to lipid homeostasis. 6-Bnz-cAMP activates PKA (protein kinase A), leading to downstream effects on cellular processes that can modulate ARK-2 activity. BAY 41-2272, a soluble guanylate cyclase (sGC) activator, stimulates sGC, increasing cGMP levels that can modulate ARK-2 through downstream effects on cGMP signaling.

Resveratrol, a sirtuin activator, influences cellular metabolism and can modulate ARK-2 activity through downstream effects on metabolism and energy homeostasis. PMA (4-Phorbol 12-myristate 13-acetate), a protein kinase C (PKC) activator, affects various signaling pathways and can modulate ARK-2 through downstream effects on PKC-mediated signaling. Sodium orthovanadate inhibits protein tyrosine phosphatase (PTP), leading to increased tyrosine phosphorylation that can modulate ARK-2 activity through downstream effects on cellular processes. AICAR, an AMP-activated protein kinase (AMPK) activator, affects cellular energy sensing and can modulate ARK-2 through downstream effects on cellular metabolism and signaling. Isoproterenol, a β-adrenergic receptor agonist, activates β-adrenergic receptors, leading to increased cAMP levels that can modulate ARK-2 through downstream effects on cAMP signaling. Collectively, these activators provide valuable tools for understanding the intricate regulatory mechanisms governing ARK-2 in cellular processes.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Adenylyl cyclase activator influencing cAMP signaling. Forskolin stimulates cAMP production, leading to the activation of downstream pathways that modulate ARK-2 activity.

A-769662

844499-71-4sc-203790
sc-203790A
sc-203790B
sc-203790C
sc-203790D
10 mg
50 mg
100 mg
500 mg
1 g
$184.00
$741.00
$1076.00
$3417.00
$5304.00
23
(2)

AMP-activated protein kinase (AMPK) activator affecting cellular energy sensing. A769662 activates AMPK, which can modulate ARK-2 through indirect downstream effects on cellular metabolism and signaling.

GW501516

317318-70-0sc-202642
sc-202642A
1 mg
5 mg
$82.00
$179.00
28
(3)

Peroxisome proliferator-activated receptor delta (PPARδ) agonist affecting lipid metabolism. GW501516 activates PPARδ, potentially influencing ARK-2 activity through downstream effects on cellular processes related to lipid homeostasis.

Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt

30275-80-0sc-300167
10 µmol
$324.00
1
(1)

PKA (protein kinase A) activator influencing cAMP-dependent pathways. 6-Bnz-cAMP activates PKA, leading to downstream effects on cellular processes that can modulate ARK-2 activity.

BAY 41-2272

256376-24-6sc-202491
sc-202491A
5 mg
25 mg
$238.00
$728.00
4
(0)

Soluble guanylate cyclase (sGC) activator affecting cGMP signaling. BAY 41-2272 stimulates sGC, leading to increased cGMP levels that can modulate ARK-2 through downstream effects on cellular processes related to cGMP signaling.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Sirtuin activator influencing cellular metabolism. Resveratrol activates sirtuins, which can modulate ARK-2 activity through downstream effects on cellular processes related to metabolism and energy homeostasis.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Protein kinase C (PKC) activator affecting various signaling pathways. PMA activates PKC, which can modulate ARK-2 through downstream effects on cellular processes related to PKC-mediated signaling.

Sodium Orthovanadate

13721-39-6sc-3540
sc-3540B
sc-3540A
5 g
10 g
50 g
$49.00
$57.00
$187.00
142
(4)

Protein tyrosine phosphatase (PTP) inhibitor affecting signaling cascades. Sodium orthovanadate inhibits PTP, leading to increased tyrosine phosphorylation that can modulate ARK-2 activity through downstream effects on cellular processes.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AMP-activated protein kinase (AMPK) activator affecting cellular energy sensing. AICAR activates AMPK, which can modulate ARK-2 through downstream effects on cellular metabolism and signaling.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

β-adrenergic receptor agonist influencing cAMP signaling. Isoproterenol activates β-adrenergic receptors, leading to increased cAMP levels that can modulate ARK-2 through downstream effects on cellular processes related to cAMP signaling.