ARK-2 activators encompass a variety of chemicals that modulate the activity of ARK-2, providing insights into mechanisms for cellular regulation. Forskolin, a potent adenylyl cyclase activator, stimulates cAMP production, leading to the activation of downstream pathways that modulate ARK-2 activity. A769662, an AMP-activated protein kinase (AMPK) activator, affects cellular energy sensing and can modulate ARK-2 through downstream effects on cellular metabolism and signaling. GW501516, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, activates PPARδ, influencing ARK-2 activity through downstream effects on cellular processes related to lipid homeostasis. 6-Bnz-cAMP activates PKA (protein kinase A), leading to downstream effects on cellular processes that can modulate ARK-2 activity. BAY 41-2272, a soluble guanylate cyclase (sGC) activator, stimulates sGC, increasing cGMP levels that can modulate ARK-2 through downstream effects on cGMP signaling.
Resveratrol, a sirtuin activator, influences cellular metabolism and can modulate ARK-2 activity through downstream effects on metabolism and energy homeostasis. PMA (4-Phorbol 12-myristate 13-acetate), a protein kinase C (PKC) activator, affects various signaling pathways and can modulate ARK-2 through downstream effects on PKC-mediated signaling. Sodium orthovanadate inhibits protein tyrosine phosphatase (PTP), leading to increased tyrosine phosphorylation that can modulate ARK-2 activity through downstream effects on cellular processes. AICAR, an AMP-activated protein kinase (AMPK) activator, affects cellular energy sensing and can modulate ARK-2 through downstream effects on cellular metabolism and signaling. Isoproterenol, a β-adrenergic receptor agonist, activates β-adrenergic receptors, leading to increased cAMP levels that can modulate ARK-2 through downstream effects on cAMP signaling. Collectively, these activators provide valuable tools for understanding the intricate regulatory mechanisms governing ARK-2 in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Adenylyl cyclase activator influencing cAMP signaling. Forskolin stimulates cAMP production, leading to the activation of downstream pathways that modulate ARK-2 activity. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
AMP-activated protein kinase (AMPK) activator affecting cellular energy sensing. A769662 activates AMPK, which can modulate ARK-2 through indirect downstream effects on cellular metabolism and signaling. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $82.00 $179.00 | 28 | |
Peroxisome proliferator-activated receptor delta (PPARδ) agonist affecting lipid metabolism. GW501516 activates PPARδ, potentially influencing ARK-2 activity through downstream effects on cellular processes related to lipid homeostasis. | ||||||
Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt | 30275-80-0 | sc-300167 | 10 µmol | $324.00 | 1 | |
PKA (protein kinase A) activator influencing cAMP-dependent pathways. 6-Bnz-cAMP activates PKA, leading to downstream effects on cellular processes that can modulate ARK-2 activity. | ||||||
BAY 41-2272 | 256376-24-6 | sc-202491 sc-202491A | 5 mg 25 mg | $238.00 $728.00 | 4 | |
Soluble guanylate cyclase (sGC) activator affecting cGMP signaling. BAY 41-2272 stimulates sGC, leading to increased cGMP levels that can modulate ARK-2 through downstream effects on cellular processes related to cGMP signaling. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Sirtuin activator influencing cellular metabolism. Resveratrol activates sirtuins, which can modulate ARK-2 activity through downstream effects on cellular processes related to metabolism and energy homeostasis. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Protein kinase C (PKC) activator affecting various signaling pathways. PMA activates PKC, which can modulate ARK-2 through downstream effects on cellular processes related to PKC-mediated signaling. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Protein tyrosine phosphatase (PTP) inhibitor affecting signaling cascades. Sodium orthovanadate inhibits PTP, leading to increased tyrosine phosphorylation that can modulate ARK-2 activity through downstream effects on cellular processes. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AMP-activated protein kinase (AMPK) activator affecting cellular energy sensing. AICAR activates AMPK, which can modulate ARK-2 through downstream effects on cellular metabolism and signaling. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
β-adrenergic receptor agonist influencing cAMP signaling. Isoproterenol activates β-adrenergic receptors, leading to increased cAMP levels that can modulate ARK-2 through downstream effects on cellular processes related to cAMP signaling. | ||||||