You may not log in without verifying your email address.
Please check your email (including your spam email) for the Welcome message that was sent.
Sodium orthovanadate is a commonly used general inhibitor for protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. Sodium orthovanadate acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium orthovanadate is also an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK).
1. Gordon, J.A., 1991. Meth. Enzymol. 201: 477-482. PMID: 1943774
2. Huyer, G., et al. 1997. J. Biol. Chem. 272: 843-851. PMID: 8995372
See how others have used Sodium Orthovanadate. Click on the entry to view the PubMed entry .
PMID: # 30917306 Figard, L.|Zheng, L.|Biel, N.|Xue, Z.|Seede, H.|Coleman, S.|Golding, I.|Sokac, AM.| et al. 2019. Cell Rep. 26: 3493-3501.e4.
PMID: # 31441677 2019. Am. J. Physiol. Heart Circ. Physiol. 29: 818-26.
PMID: # 30322148 Osa-Andrews, B.|Tan, KW.|Sampson, A.|Iram, SH.| et al. 2018. Pharmaceutics. 10:
PMID: # 28225025 Tóth, A.|Zajta, E.|Csonka, K.|Vágvölgyi, C.|Netea, MG.|Gácser, A.| et al. 2017. Sci Rep. 7: 43129.
PMID: # 28626608 Song, L. et al. 2017. PeerJ. 5: e3418.
PMID: # 27760898 Mitsui, T.|Ishida, M.|Izawa, M.|Arita, J.| et al. 2017. Endocr. J. 64: 103-115.
PMID: # 26934553 Webber, JP. et al. 2016. Oncotarget.
PMID: # 27113095 Boriushkin, E. et al. 2016. Sci Rep. 6: 25013.
PMID: # 27053106 Popa, IL. et al. 2016. J. Biol. Chem.
PMID: # 26981571 Scholz, G. et al. 2016. EBioMedicine. 4: 50-61.
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.