ACAT Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Enniatin B | 917-13-5 | sc-202150 | 1 mg | $300.00 | 4 | |
Enniatin B acts as an ACAT, demonstrating a unique ability to modulate lipid metabolism through its interaction with acyl-CoA:cholesterol acyltransferase. This compound influences the esterification of cholesterol, impacting lipid droplet formation and cellular lipid homeostasis. Its kinetic profile reveals a selective inhibition mechanism, altering substrate binding dynamics and enhancing the accumulation of free cholesterol in cellular compartments, thereby affecting overall lipid dynamics. | ||||||
Pellitorine | 18836-52-7 | sc-391071 sc-391071A sc-391071B | 1 mg 5 mg 10 mg | $160.00 $640.00 $1009.00 | ||
Pellitorine functions as an ACAT, exhibiting a distinctive capacity to influence lipid biosynthesis by interacting with acyl-CoA:cholesterol acyltransferase. This compound alters the acylation process of cholesterol, thereby affecting lipid droplet dynamics and cellular lipid distribution. Its reaction kinetics suggest a competitive inhibition model, modifying the affinity for substrates and promoting the retention of unesterified cholesterol, which can significantly impact cellular lipid regulation. | ||||||
Auraptene | 495-02-3 | sc-202477 sc-202477A | 5 mg 25 mg | $45.00 $60.00 | ||
Auraptene acts as an ACAT, demonstrating a unique ability to modulate lipid metabolism through its interaction with acyl-CoA:cholesterol acyltransferase. This compound influences the esterification of cholesterol, leading to alterations in lipid droplet formation and distribution within cells. Its kinetic profile indicates a non-competitive inhibition mechanism, which affects substrate binding dynamics and promotes the accumulation of free cholesterol, thereby impacting overall lipid homeostasis. | ||||||
CI 976 | 114289-47-3 | sc-203892B sc-203892 sc-203892A | 5 mg 10 mg 50 mg | $107.00 $185.00 $759.00 | 4 | |
CI 976 functions as an ACAT, exhibiting a distinctive capacity to influence lipid dynamics by interacting with acyl-CoA:cholesterol acyltransferase. This compound alters the acylation process of cholesterol, affecting lipid droplet morphology and cellular distribution. Its reaction kinetics suggest a mixed inhibition pattern, which modifies the affinity for substrates and enhances the release of unesterified cholesterol, thereby reshaping lipid balance within cellular environments. | ||||||
A 922500 | 959122-11-3 | sc-203793 | 10 mg | $265.00 | 2 | |
A 922500 functions as an ACAT by selectively modulating the acyl-CoA:cholesterol acyltransferase enzyme, influencing lipid storage and mobilization. Its unique molecular architecture allows for enhanced binding interactions, promoting a shift in lipid partitioning. The compound exhibits distinct reaction kinetics, affecting the rate of cholesterol esterification. Additionally, A 922500 alters the physical properties of lipid membranes, impacting their fluidity and organization within cellular environments. | ||||||
Penicillide | 55303-92-9 | sc-391044 | 1 mg | $160.00 | ||
Penicillide acts as an ACAT, demonstrating a unique ability to modulate lipid metabolism through its interaction with acyl-CoA:cholesterol acyltransferase. This compound influences the esterification of cholesterol, leading to alterations in lipid droplet formation and cellular lipid distribution. Its kinetic profile indicates competitive inhibition, which affects substrate binding and promotes the liberation of free cholesterol, thereby impacting overall lipid homeostasis in cells. | ||||||
YIC-C8-434 | 214265-97-1 | sc-216068 | 5 mg | $245.00 | ||
YIC-C8-434 functions as an ACAT, exhibiting a distinctive mechanism of action by selectively binding to the acyl-CoA:cholesterol acyltransferase enzyme. This interaction disrupts the normal esterification process of cholesterol, resulting in significant changes in lipid droplet dynamics and cellular lipid profiles. The compound's reaction kinetics reveal a non-competitive inhibition pattern, enhancing the release of free cholesterol and thereby influencing cellular lipid equilibrium and transport pathways. | ||||||
Terpendole E | 167427-23-8 | sc-391039 | 1 mg | $240.00 | ||
Terpendole E acts as an ACAT by engaging in specific interactions with the acyl-CoA:cholesterol acyltransferase enzyme, leading to altered lipid metabolism. Its unique structural features facilitate a competitive inhibition mechanism, which modifies the esterification of cholesterol. This compound also influences lipid droplet morphology and distribution, impacting cellular lipid homeostasis. The distinct binding affinity and kinetics of Terpendole E contribute to its role in regulating lipid dynamics within cells. | ||||||
Oleyl Anilide | 5429-85-6 | sc-205419 sc-205419A | 5 mg 10 mg | $20.00 $33.00 | ||
Oleyl Anilide acts as an ACAT by engaging in specific interactions with the acyl-CoA:cholesterol acyltransferase enzyme, facilitating the transfer of acyl groups. Its structural features enable it to stabilize enzyme-substrate complexes, thereby influencing the kinetics of cholesterol esterification. The compound also modifies lipid dynamics, leading to changes in membrane composition and integrity, which can affect cellular signaling pathways and lipid metabolism. | ||||||
(3S,6R)-Lateritin | 65454-13-9 | sc-364092 | 1 mg | $214.00 | ||
(3S,6R)-Lateritin functions as an ACAT by selectively binding to the acyl-CoA:cholesterol acyltransferase enzyme, promoting acyl group transfer with high specificity. Its unique stereochemistry enhances substrate affinity, optimizing reaction rates. The compound's interactions with lipid bilayers can alter membrane fluidity, impacting cellular processes. Additionally, it may influence the distribution of lipid droplets, thereby modulating intracellular lipid homeostasis and signaling pathways. | ||||||