Date published: 2026-2-26

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ACAT Substrates

Santa Cruz Biotechnology now offers a broad range of ACAT Substrates for use in various applications. ACAT substrates are specialized compounds that serve as the specific targets for the enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT), which is vital for the esterification of cholesterol and the formation of cholesterol esters within cells. This process is crucial in the regulation of intracellular cholesterol levels and the maintenance of lipid homeostasis. In scientific research, ACAT substrates are essential tools for studying the mechanisms of cholesterol metabolism, lipid storage, and transport within cells. Researchers use these substrates to investigate how cholesterol esters are synthesized and how they influence cellular functions such as membrane structure, signal transduction, and energy storage. By utilizing ACAT substrates, scientists can explore the roles of cholesterol esterification in various biological systems and understand the effects of altered lipid metabolism on cellular health. These substrates are particularly valuable in studies focusing on metabolic diseases, cardiovascular health, and lipid-related disorders. The availability of high-purity ACAT substrates from Santa Cruz Biotechnology ensures that experiments can be conducted with precision and reproducibility, yielding reliable data that advance our knowledge of lipid biochemistry and cholesterol regulation. By providing a comprehensive selection of these substrates, Santa Cruz Biotechnology supports the scientific community in developing new experimental models and uncovering novel insights into the regulation of lipid metabolism and its impact on cellular physiology. View detailed information on our available ACAT Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Acetoacetyl coenzyme A sodium salt

102029-52-7sc-252348
sc-252348B
5 mg
10 mg
$478.00
$843.00
(2)

Acetoacetyl coenzyme A sodium salt acts as an ACAT by facilitating the transfer of acyl groups in lipid metabolism. Its structural conformation allows for effective binding to the enzyme, enhancing catalytic efficiency. The compound's ability to participate in diverse metabolic pathways, including ketogenesis and fatty acid synthesis, underscores its role in energy homeostasis. Furthermore, its interactions with coenzymes can influence reaction kinetics, promoting efficient substrate conversion.