Acetoacetyl coenzyme A sodium salt may be used as a substrate for a number of enzymes including; ACAT(acetoacetyl-CoA thiolase (EC 2.3.1)) which produces acetyl-CoA in reverse condensation reaction; mHMGCS and cHMGCS (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces 3-hydroxy-3-methylglutaryl (HMG)-CoA in the mevalonate pathway leading to terpenoid biosynthesis. Acetoacetyl-CoA is also a precursor of poly-beta-hydroxybutyrate polymers in microorganisms.
W.H. Salam et al. Biochem. J. 258, 563, (1989) C.A. Clark J. Chem. Soc., Chem. Commun., 1568, (1985)
Soluble in water (50 mg/ml).
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Rated 5 out of
McQualterMcQualter, RB. et al. (PubMed 25532451) reported that the use of an Acetoacetyl-CoA synthase in place of a -ketothiolase enhanced poly-3-hydroxybutyrate production in sugarcane mesophyll cells. -SCBT Publication Review
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