Molecular structure of Acetoacetyl coenzyme A sodium salt, CAS Number: 102029-52-7
Acetoacetyl coenzyme A sodium salt (CAS 102029-52-7)
Alternate Names:
Acetoacetyl-CoA•xNa
Application:
Acetoacetyl coenzyme A sodium salt is A substrate used by a number of enzymes including ACAT (acetoacetyl-CoA thiolase)
CAS Number:
102029-52-7
Purity:
≥90%
Molecular Weight:
851.61
Molecular Formula:
C25H40N7O18P3S•xNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Acetoacetyl coenzyme A sodium salt may be used as a substrate for a number of enzymes including ACAT(acetoacetyl-CoA thiolase (EC 2.3.1)) which produces acetyl-CoA in reverse condensation reaction mHMGCS and cHMGCS (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces 3-hydroxy-3-methylglutaryl (HMG)-CoA in the mevalonate pathway leading to terpenoid biosynthesis. Acetoacetyl-CoA is also a precursor of poly-beta-hydroxybutyrate polymers in microorganisms.
Acetoacetyl coenzyme A sodium salt (CAS 102029-52-7) References
- Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. | Okamura, E., et al. 2010. Proc Natl Acad Sci U S A. 107: 11265-70. PMID: 20534558
- Stimulation of hepatic cholesterol biosynthesis by fatty acids. Effects of oleate on cytoplasmic acetoacetyl-CoA thiolase, acetoacetyl-CoA synthetase and hydroxymethylglutaryl-CoA synthase. | Salam, WH., et al. 1989. Biochem J. 258: 563-8. PMID: 2565110
- LC-MS/MS-based analysis of coenzyme A and short-chain acyl-coenzyme A thioesters. | Neubauer, S., et al. 2015. Anal Bioanal Chem. 407: 6681-8. PMID: 26168961
- An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation. | Carroll, RG., et al. 2018. J Biol Chem. 293: 5509-5521. PMID: 29463677
- Convergent changes in muscle metabolism depend on duration of high-altitude ancestry across Andean waterfowl. | Dawson, NJ., et al. 2020. Elife. 9: PMID: 32729830
- Biosynthesis Of Nonactin. The Role Of Acetoacetyl-Coa In The Formation Nonactic Acid | Carole A. Clark and John A. Robinson. 1985. J. Chem. Soc., Chem. Commun. 22: 1568-1569.
Substrate of:
ACAT, cHMGCS, Enzyme, and mHMGCS.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acetoacetyl coenzyme A sodium salt, 5 mg | sc-252348 | 5 mg | $469.00 | |||
Acetoacetyl coenzyme A sodium salt, 10 mg | sc-252348B | 10 mg | $826.00 |