Date published: 2026-6-26

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ACAT Antibodies

Santa Cruz Biotechnology delivers a wide array of ACAT monoclonal antibodies for studying Acyl-CoA:cholesterol acyltransferase (ACAT), a key enzyme involved in cholesterol metabolism. ACAT monoclonal antibodies are effective for multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). ACAT plays a crucial role in the esterification of cholesterol, which is essential for maintaining cellular cholesterol homeostasis and regulating lipid metabolism. Dysregulation of ACAT activity has been implicated in several diseases, including atherosclerosis and neurodegenerative disorders, making it a significant target for therapeutic intervention. Understanding ACAT function through molecular research can provide insights into essential biological processes. Researchers worldwide utilize ACAT monoclonal antibodies to investigate cholesterol metabolism pathways and their impact on various diseases. Advanced research techniques with ACAT monoclonal antibodies enable detailed examination of cellular mechanisms and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies for ACAT research support scientists in advancing our understanding of cholesterol metabolism and its role in human health.

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ACAT Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ACAT-1 Antibody (AT15E5)

sc-517387mouse IgG1 κ34-427 (h)WB, IP, IF, ELISAh
1
(3)

ACAT-2 Antibody (4A5)

sc-293307mouse IgG2a κFL (h)WB, IP, ELISAm, r, h
1
(1)

ACAT siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ACAT-1 siRNA (h)

sc-96390hGene SilencingN/A
5
(0)

ACAT-1 shRNA Plasmid (h)

sc-96390-SHhGene SilencingPuromycin
5
(0)

ACAT-1 shRNA (h) Lentiviral Particles

sc-96390-VhGene SilencingPuromycin
5
(0)

ACAT-1 siRNA (m)

sc-108039mGene SilencingN/A
1
(0)

ACAT-1 shRNA Plasmid (m)

sc-108039-SHmGene SilencingPuromycin
1
(0)

ACAT-1 shRNA (m) Lentiviral Particles

sc-108039-VmGene SilencingPuromycin
1
(0)

ACAT-2 siRNA (h)

sc-61908hGene SilencingN/A0
(0)

ACAT-2 shRNA Plasmid (h)

sc-61908-SHhGene SilencingPuromycin0
(0)

ACAT-2 shRNA (h) Lentiviral Particles

sc-61908-VhGene SilencingPuromycin0
(0)

ACAT-2 siRNA (m)

sc-61909mGene SilencingN/A
1
(0)

ACAT-2 shRNA Plasmid (m)

sc-61909-SHmGene SilencingPuromycin
1
(0)

ACAT-2 shRNA (m) Lentiviral Particles

sc-61909-VmGene SilencingPuromycin
1
(0)

ACAT-3 siRNA (m)

sc-140795mGene SilencingN/A0
(0)

ACAT-3 shRNA Plasmid (m)

sc-140795-SHmGene SilencingPuromycin0
(0)

ACAT-3 shRNA (m) Lentiviral Particles

sc-140795-VmGene SilencingPuromycin0
(0)

ACAT CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

ACAT-1 CRISPR/Cas9 KO Plasmid (h)

sc-402300Gene Knockouth0
(0)

ACAT-1 HDR Plasmid (h)

sc-402300-HDRHomology Directed Repairh0
(0)

ACAT CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

ACAT-1 Double Nickase Plasmid (h)

sc-402300-NICGene Knockouth0
(0)

ACAT-1 Double Nickase Plasmid (h2)

sc-402300-NIC-2Gene Knockouth0
(0)

ACAT-2 Double Nickase Plasmid (h)

sc-403419-NICGene Knockouth0
(0)

ACAT-2 Double Nickase Plasmid (h2)

sc-403419-NIC-2Gene Knockouth0
(0)

ACAT CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

ACAT-1 CRISPR Activation Plasmid (h)

sc-402300-ACTGene Activationh0
(0)

ACAT-1 Lentiviral Activation Particles (h)

sc-402300-LACGene Activationh0
(0)

ACAT-2 CRISPR Activation Plasmid (h)

sc-403419-ACTGene Activationh0
(0)