Date published: 2025-12-4

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Penicillide (CAS 55303-92-9)

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Alternate Names:
Vermixocin A; Antibiotic AS 186A; Antibiotic MC 140
Application:
Penicillide is a potential ACAT, Calpain, and Oxytocin Receptor inhibitor
CAS Number:
55303-92-9
Molecular Weight:
372.4
Molecular Formula:
C21H24O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Penicillide is an ACAT (acyl-CoA-cholesterol acyltransferase), Calpain, and Oxytocin Receptor inhibitor. Suggested to display anticancer and plant growth inhibitory properties.


Penicillide (CAS 55303-92-9) References

  1. Vermixocins A and B, two novel metabolites from Penicillium vermiculatum.  |  Proksa, B., et al. 1992. J Antibiot (Tokyo). 45: 1268-72. PMID: 1399847
  2. 1H and 13C NMR assignments for 6-demethylvermistatin and two penicillide derivatives from the mangrove fungus Guignardia sp. (No. 4382) from the South China Sea.  |  Xia, XK., et al. 2008. Magn Reson Chem. 46: 693-6. PMID: 18338749
  3. Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. III. Chemical modification of purpactin A.  |  Nishida, H., et al. 1991. J Antibiot (Tokyo). 44: 152-9. PMID: 2010355
  4. Enhancement of metabolites productivity of Penicillium pinophilum FKI-5653, by co-culture with Trichoderma harzianum FKI-5655.  |  Nonaka, K., et al. 2011. J Antibiot (Tokyo). 64: 769-74. PMID: 22008698
  5. Acetylcholinesterase inhibitors from a marine fungus Talaromyces sp. strain LF458.  |  Wu, B., et al. 2015. Mar Biotechnol (NY). 17: 110-9. PMID: 25108548
  6. Secondary Metabolites Produced by an Endophytic Fungus Pestalotiopsis sydowiana and Their 20S Proteasome Inhibitory Activities.  |  Xia, X., et al. 2016. Molecules. 21: PMID: 27447600
  7. New penicillide derivatives isolated from Penicillium simplicissimum.  |  Komai, SI., et al. 2006. J Nat Med. 60: 185-190. PMID: 29435879
  8. Two marine natural products, penicillide and verrucarin J, are identified from a chemical genetic screen for neutral lipid accumulation effectors in Phaeodactylum tricornutum.  |  Yu, M., et al. 2020. Appl Microbiol Biotechnol. 104: 2731-2743. PMID: 32002603
  9. Antibacterial Secondary Metabolites from Marine-Derived Fungus Aspergillus sp. IMCASMF180035.  |  Song, F., et al. 2021. Antibiotics (Basel). 10: PMID: 33916658
  10. Five Tetramic Acid Derivatives Isolated from the Iranian Fungus Colpoma quercinum CCTU A372.  |  Primahana, G., et al. 2021. Biomolecules. 11: PMID: 34067463
  11. Anthraquinones, Diphenyl Ethers, and Their Derivatives from the Culture of the Marine Sponge-Associated Fungus Neosartorya spinosa KUFA 1047.  |  de Sá, JDM., et al. 2021. Mar Drugs. 19: PMID: 34436296
  12. New Antibacterial Secondary Metabolites from a Marine-Derived Talaromyces sp. Strain BTBU20213036.  |  Song, F., et al. 2022. Antibiotics (Basel). 11: PMID: 35203824
  13. AS-186 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase from Penicillium asperosporum KY1635.  |  Kuroda, K., et al. 1994. J Antibiot (Tokyo). 47: 16-22. PMID: 8119857

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Penicillide, 1 mg

sc-391044
1 mg
$160.00