CEACAM19 Activators
CEACAM19 Activators are a collection of chemical compounds that are known to enhance the functional activity of CEACAM19 through specific signaling pathways and biological processes. Forskolin, through its action on adenylate cyclase, increases cAMP levels and activates PKA, potentially resulting in the phosphorylation and functional enhancement of CEACAM19 within cell signaling networks. 8-Br-cAMP, being a cAMP analog, similarly activates PKA, which can further phosphorylate and enhance the activity of CEACAM19. Isoproterenol, as a β-adrenergic agonist, also raises intracellular cAMP levels, thereby activating PKA and influencing CEACAM19 activity.
CEACAM19 Activators include a diverse array of compounds that indirectly enhance the activity of CEACAM19 through various signaling pathways. Forskolin, by activating adenylate cyclase, induces an increase in intracellular cAMP, which in turn activates PKA. This kinase can phosphorylate and thus promote the functional activity of CEACAM19 in cAMP-dependent pathways. Similarly, 8-Br-cAMP, a stable cAMP analog, and Isoproterenol, through β-adrenergic receptor stimulation, lead to PKA activation and may enhance the phosphorylation state and activity of CEACAM19. Ionomycin, by increasing intracellular calcium levels, can activate calcium-dependent kinases that also have the potential to phosphorylate and enhance CEACAM19 function within calcium-signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $108.00 $169.00 $295.00 $561.00 $835.00 | 2 | |
8-Br-cAMP is a cell-permeable cAMP analog that activates PKA. Activation of PKA can result in phosphorylation and activation of downstream proteins, including CEACAM19, thereby enhancing its activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a β-adrenergic agonist that increases intracellular cAMP levels, leading to PKA activation. PKA can then phosphorylate and activate CEACAM19 as part of the cAMP-dependent signaling pathway. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, which can activate calcium-dependent protein kinases. These kinases can modulate CEACAM19 activity by influencing its phosphorylation state or its interaction with other proteins in calcium-dependent signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is an activator of protein kinase C (PKC), which can phosphorylate a range of target proteins. PKC-mediated phosphorylation can enhance the activity of CEACAM19 in cellular processes that are regulated by PKC activity. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $53.00 $88.00 | 6 | |
Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), can influence the arachidonic acid pathway and modulate the activity of various kinases and phosphatases. This modulation can indirectly affect the phosphorylation status of CEACAM19, leading to its enhanced activity in anti-inflammatory signaling pathways. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine, through its receptor-mediated signaling, activates phospholipase C, which results in the formation of inositol trisphosphate (IP3) and diacylglycerol (DAG). The downstream effect of this signaling can lead to the activation of kinases that modulate CEACAM19 activity. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $37.00 $104.00 $580.00 $1196.00 | 10 | |
Oleic acid is a monounsaturated fatty acid that can be incorporated into cell membranes, affecting membrane fluidity and associated signaling pathways. Changes in membrane composition can influence the conformation and function of membrane proteins, potentially enhancing the activity of CEACAM19. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a derivative of vitamin A, influences gene expression by activating nuclear receptors. This can lead to altered protein expression levels and modifications in signaling pathways that indirectly enhance the functional activity of CEACAM19. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin binds to its receptor and activates the PI3K/AKT signaling pathway, which can lead to the translocation of glucose transporters to the cell membrane and influence other signaling proteins. This can indirectly affect CEACAM19 activity in metabolic pathways. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc sulfate can provide zinc ions, which are essential cofactors for many enzymes, including kinases and phosphatases that modulate signaling pathways. The availability of zinc can affect the phosphorylation state of proteins like CEACAM19, enhancing its activity. | ||||||