Date published: 2026-7-15

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MEK Antibodies

Santa Cruz Biotechnology features a diverse variety of MEK Antibodies for research focused on understanding the MAPK signaling pathway. MEK Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MEK, or mitogen-activated protein kinase kinase, plays a crucial role in cell signaling, particularly in the regulation of cell proliferation, differentiation, and survival. By activating ERK (extracellular signal-regulated kinase), MEK is integral to the transmission of signals from growth factors and other extracellular stimuli, making it a key player in cancer research and therapeutic development. Understanding MEK's function and regulation is essential for elucidating the mechanisms underlying various diseases, particularly those related to uncontrolled cell growth. MEK research has revealed significant insights into cellular communication pathways and their impact on disease progression. Ongoing studies continue to uncover new aspects of MEK's involvement in cellular processes and disease states. Advanced research techniques have highlighted MEK's significance in multiple biological pathways. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of MEK's role in cellular signaling and disease mechanisms.

SEE ALSO...

MEK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MEK-1 Antibody (H-8)

sc-6250mouse IgG2b κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
94
(33)

MEK-1 Antibody (A-8)

sc-365800mouse IgG2a κC-Terminal (r)WB, IP, IF, IHC(P), ELISAm, r, h
1
(4)

MEK-1/2 Antibody (9G3)

sc-81504mouse IgG2a(h)WB, IPm, r, h and canine
51
(8)

MEK-2 Antibody (A-1)

sc-13159mouse IgG2a κ6-25 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(12)

MEK-2 Antibody (8E8)

sc-81473mouse IgG1N-Terminal (h)WB, IPm, r, h and canine
2
(2)

MEK-2 Antibody (96)

sc-136261mouse IgG2a1-110 (r)WB, IP, IFm, r, h and canine
1
(3)

MEK-3 Antibody (B-5)

sc-271779mouse IgG3 κ32-61 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(6)

MEK-3 Antibody (5F7)

sc-81474mouse IgG1(h)WB, IP, IFm, r, h and canine

new

(2)

MEK-3 Antibody (B-2)

sc-376627mouse IgM κ291-320 (h)WB, IP, IF, ELISAm, r, h
1
(2)

MEK-3/6 Antibody (B-1)

sc-136982mouse IgG2b κ229-318 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(7)

MEK-3/6 Antibody (D-3)

sc-133230mouse IgG2b κ229-318 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(3)

MEK-3/6 Antibody (E-3)

sc-137106mouse IgG2a κ229-318 (h)WB, IP, IF, ELISAm, r, h

new

(2)

MEK-4 Antibody (G-7)

sc-376838mouse IgG1 κ43-79 (m)WB, IP, IF, IHC(P), ELISAm, r, h
3
(7)

MEK-4 Antibody (G-6)

sc-166168mouse IgG2b κ302-399 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(3)

MEK-5 Antibody (E-3)

sc-365198mouse IgG1 κ351-444 (h)WB, IP, IF, ELISAm, r, h
1
(1)

MEK-6 Antibody (C-1)

sc-166746mouse IgG2b κ297-315 (h)WB, IP, IF, ELISAm, r, h

new

(4)

MEK-6 Antibody (D-8)

sc-166727mouse IgG1 κC-terminal (h)WB, IP, IF, ELISAm, r, h

new

(1)

MEK-6 Antibody (G-12)

sc-166728mouse IgG2b κN-terminal (h)WB, IP, IF, ELISAm, r, h

new

(2)

MEK-7 Antibody (E-7)

sc-25288mouse IgG2a κ1-160 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(7)

Phospho-Specific MEK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-MEK-1 Antibody (B-4)

sc-271914mouse IgG1 κSer 298 (h)WB, IP, IF, ELISAm, r, h
13
(9)

p-MEK-1 Antibody (47.Ser 222)

sc-136542mouse IgASer 222 (h)WB, IP, ELISAm, r, h
4
(5)

p-MEK-1/2 Antibody (7E10)

sc-81503mouse IgG1Ser 218/222 (h)WB, IPm, r, h and canine
44
(5)

p-MEK-3/6 Antibody (B-9)

sc-8407mouse IgG1 κSer 189/207 (h)WB, IP, IF, IHC(P), ELISAm, r, h
22
(13)

MEK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MEK-1 siRNA (h)

sc-29396hGene SilencingN/A
19
(0)

MEK-1 shRNA Plasmid (h)

sc-29396-SHhGene SilencingPuromycin
19
(0)

MEK-1 shRNA (h) Lentiviral Particles

sc-29396-VhGene SilencingPuromycin
19
(0)

MEK-1 siRNA (m)

sc-35904mGene SilencingN/A
5
(0)

MEK-1 shRNA Plasmid (m)

sc-35904-SHmGene SilencingPuromycin
5
(0)

MEK-1 shRNA (m) Lentiviral Particles

sc-35904-VmGene SilencingPuromycin
5
(0)

MEK-1 siRNA (bovine)

sc-156180bovineGene SilencingN/A0
(0)

MEK-2 siRNA (h)

sc-35905hGene SilencingN/A
7
(0)

MEK-2 shRNA Plasmid (h)

sc-35905-SHhGene SilencingPuromycin
7
(0)

MEK-2 shRNA (h) Lentiviral Particles

sc-35905-VhGene SilencingPuromycin
7
(0)

MEK-2 siRNA (m)

sc-35906mGene SilencingN/A
1
(0)

MEK-2 shRNA Plasmid (m)

sc-35906-SHmGene SilencingPuromycin
1
(0)

MEK-2 shRNA (m) Lentiviral Particles

sc-35906-VmGene SilencingPuromycin
1
(0)

MEK-3 siRNA (h)

sc-35907hGene SilencingN/A
7
(0)

MEK-3 shRNA Plasmid (h)

sc-35907-SHhGene SilencingPuromycin
7
(0)

MEK-3 shRNA (h) Lentiviral Particles

sc-35907-VhGene SilencingPuromycin
7
(0)

MEK-3 siRNA (m)

sc-35908mGene SilencingN/A
2
(0)

MEK-3 shRNA Plasmid (m)

sc-35908-SHmGene SilencingPuromycin
2
(0)

MEK-3 shRNA (m) Lentiviral Particles

sc-35908-VmGene SilencingPuromycin
2
(0)

MEK-4 siRNA (h)

sc-35909hGene SilencingN/A
5
(1)

MEK-4 shRNA Plasmid (h)

sc-35909-SHhGene SilencingPuromycin
5
(1)

MEK-4 shRNA (h) Lentiviral Particles

sc-35909-VhGene SilencingPuromycin
5
(1)

MEK-4 siRNA (m)

sc-35910mGene SilencingN/A
3
(0)

MEK-4 shRNA Plasmid (m)

sc-35910-SHmGene SilencingPuromycin
3
(0)

MEK-4 shRNA (m) Lentiviral Particles

sc-35910-VmGene SilencingPuromycin
3
(0)

MEK-5 siRNA (h)

sc-35911hGene SilencingN/A
2
(0)

MEK-5 shRNA Plasmid (h)

sc-35911-SHhGene SilencingPuromycin
2
(0)

MEK-5 shRNA (h) Lentiviral Particles

sc-35911-VhGene SilencingPuromycin
2
(0)

MEK-5 siRNA (m)

sc-35912mGene SilencingN/A
1
(0)

MEK-5 shRNA Plasmid (m)

sc-35912-SHmGene SilencingPuromycin
1
(0)

MEK-5 shRNA (m) Lentiviral Particles

sc-35912-VmGene SilencingPuromycin
1
(0)

MEK-6 siRNA (h)

sc-35913hGene SilencingN/A
5
(0)

MEK-6 shRNA Plasmid (h)

sc-35913-SHhGene SilencingPuromycin
5
(0)

MEK-6 shRNA (h) Lentiviral Particles

sc-35913-VhGene SilencingPuromycin
5
(0)

MEK-6 siRNA (m)

sc-35914mGene SilencingN/A
1
(0)

MEK-6 shRNA Plasmid (m)

sc-35914-SHmGene SilencingPuromycin
1
(0)

MEK-6 shRNA (m) Lentiviral Particles

sc-35914-VmGene SilencingPuromycin
1
(0)

MEK-7 siRNA (h)

sc-35915hGene SilencingN/A
1
(0)

MEK-7 shRNA Plasmid (h)

sc-35915-SHhGene SilencingPuromycin
1
(0)

MEK-7 shRNA (h) Lentiviral Particles

sc-35915-VhGene SilencingPuromycin
1
(0)

MEK-7 siRNA (m)

sc-35916mGene SilencingN/A
1
(0)

MEK-7 shRNA Plasmid (m)

sc-35916-SHmGene SilencingPuromycin
1
(0)

MEK-7 shRNA (m) Lentiviral Particles

sc-35916-VmGene SilencingPuromycin
1
(0)

MEK-3/6 siRNA (h)

sc-43924hGene SilencingN/A
1
(0)

MEK-3/6 shRNA Plasmid (h)

sc-43924-SHhGene SilencingPuromycin
1
(0)

MEK-3/6 shRNA (h) Lentiviral Particles

sc-43924-VhGene SilencingPuromycin
1
(0)

MEK Proteins

Empty Table HeaderProduct NameCATALOG #AmountSpeciesCitationsRATING

MEK-1 (FL)

sc-402550 µgh
17
(0)

MEK CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MEK-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400397-KO-2Gene Knockouth0
(0)

MEK-1 HDR Plasmid (h2)

sc-400397-HDR-2Homology Directed Repairh0
(0)

MEK-1 CRISPR/Cas9 KO Plasmid (m)

sc-424031Gene Knockoutm0
(0)

MEK-1 HDR Plasmid (m)

sc-424031-HDRHomology Directed Repairm0
(0)

MEK-2 HDR Plasmid (h)

sc-402732-HDRHomology Directed Repairh0
(0)

MEK-3 CRISPR/Cas9 KO Plasmid (h)

sc-401297Gene Knockouth0
(0)

MEK-3 HDR Plasmid (h)

sc-401297-HDRHomology Directed Repairh0
(0)

MEK-4 CRISPR/Cas9 KO Plasmid (h)

sc-401459Gene Knockouth0
(0)

MEK-4 HDR Plasmid (h)

sc-401459-HDRHomology Directed Repairh0
(0)

MEK-4 HDR Plasmid (m)

sc-424034-HDRHomology Directed Repairm0
(0)

MEK-5 CRISPR/Cas9 KO Plasmid (h)

sc-401688Gene Knockouth0
(0)

MEK-5 HDR Plasmid (h)

sc-401688-HDRHomology Directed Repairh0
(0)

MEK-5 CRISPR/Cas9 KO Plasmid (m)

sc-423906Gene Knockoutm0
(0)

MEK-5 HDR Plasmid (m)

sc-423906-HDRHomology Directed Repairm0
(0)

MEK-7 CRISPR/Cas9 KO Plasmid (h)

sc-402363Gene Knockouth0
(0)

MEK CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MEK-1 Double Nickase Plasmid (h)

sc-400397-NICGene Knockouth0
(0)

MEK-1 Double Nickase Plasmid (h2)

sc-400397-NIC-2Gene Knockouth0
(0)

MEK-1 Double Nickase Plasmid (m)

sc-424031-NICGene Knockoutm0
(0)

MEK-1 Double Nickase Plasmid (m2)

sc-424031-NIC-2Gene Knockoutm0
(0)

MEK-4 Double Nickase Plasmid (h)

sc-401459-NICGene Knockouth0
(0)

MEK-4 Double Nickase Plasmid (h2)

sc-401459-NIC-2Gene Knockouth0
(0)

MEK-5 Double Nickase Plasmid (h)

sc-401688-NICGene Knockouth0
(0)

MEK-5 Double Nickase Plasmid (h2)

sc-401688-NIC-2Gene Knockouth0
(0)

MEK-5 Double Nickase Plasmid (m)

sc-423906-NICGene Knockoutm0
(0)

MEK-5 Double Nickase Plasmid (m2)

sc-423906-NIC-2Gene Knockoutm0
(0)

MEK-7 Double Nickase Plasmid (h)

sc-402363-NICGene Knockouth0
(0)

MEK-7 Double Nickase Plasmid (h2)

sc-402363-NIC-2Gene Knockouth0
(0)

MEK CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

MEK-1 CRISPR Activation Plasmid (h)

sc-400397-ACTGene Activationh0
(0)

MEK-1 CRISPR Activation Plasmid (h2)

sc-400397-ACT-2Gene Activationh0
(0)

MEK-2 CRISPR Activation Plasmid (h)

sc-402732-ACTGene Activationh0
(0)

MEK-2 CRISPR Activation Plasmid (h2)

sc-402732-ACT-2Gene Activationh0
(0)

MEK-4 CRISPR Activation Plasmid (h)

sc-401459-ACTGene Activationh0
(0)

MEK-4 CRISPR Activation Plasmid (h2)

sc-401459-ACT-2Gene Activationh0
(0)

MEK-5 CRISPR Activation Plasmid (h)

sc-401688-ACTGene Activationh0
(0)

MEK-5 CRISPR Activation Plasmid (h2)

sc-401688-ACT-2Gene Activationh0
(0)

MEK-5 Lentiviral Activation Particles (h)

sc-401688-LACGene Activationh0
(0)

MEK-5 Lentiviral Activation Particles (h2)

sc-401688-LAC-2Gene Activationh0
(0)

MEK-6 CRISPR Activation Plasmid (h)

sc-402544-ACTGene Activationh0
(0)

MEK-7 CRISPR Activation Plasmid (h)

sc-402363-ACTGene Activationh0
(0)